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IL-27 limits IL-2 production during Th1 differentiation.
Villarino AV, Stumhofer JS, Saris CJ, Kastelein RA, de Sauvage FJ, Hunter CA. Villarino AV, et al. Among authors: saris cj. J Immunol. 2006 Jan 1;176(1):237-47. doi: 10.4049/jimmunol.176.1.237. J Immunol. 2006. PMID: 16365415
Interleukin 27 negatively regulates the development of interleukin 17-producing T helper cells during chronic inflammation of the central nervous system.
Stumhofer JS, Laurence A, Wilson EH, Huang E, Tato CM, Johnson LM, Villarino AV, Huang Q, Yoshimura A, Sehy D, Saris CJ, O'Shea JJ, Hennighausen L, Ernst M, Hunter CA. Stumhofer JS, et al. Among authors: saris cj. Nat Immunol. 2006 Sep;7(9):937-45. doi: 10.1038/ni1376. Epub 2006 Aug 13. Nat Immunol. 2006. PMID: 16906166
A role for IL-27p28 as an antagonist of gp130-mediated signaling.
Stumhofer JS, Tait ED, Quinn WJ 3rd, Hosken N, Spudy B, Goenka R, Fielding CA, O'Hara AC, Chen Y, Jones ML, Saris CJ, Rose-John S, Cua DJ, Jones SA, Elloso MM, Grötzinger J, Cancro MP, Levin SD, Hunter CA. Stumhofer JS, et al. Among authors: saris cj. Nat Immunol. 2010 Dec;11(12):1119-26. doi: 10.1038/ni.1957. Epub 2010 Nov 7. Nat Immunol. 2010. PMID: 21057510 Free PMC article.
49 results