Shan B - Search Results

1

Discovery and optimization of a novel series of liver X receptor-alpha agonists.

Li L, Liu J, Zhu L, Cutler S, Hasegawa H, Shan B, Medina JC. Li L, et al. Among authors: shan b. Bioorg Med Chem Lett. 2006 Mar 15;16(6):1638-42. doi: 10.1016/j.bmcl.2005.12.015. Epub 2005 Dec 28. Bioorg Med Chem Lett. 2006. PMID: 16386417

2

Optimization of triazoles as novel and potent nonphlorizin SGLT2 inhibitors.

Du X, Lizarzaburu M, Turcotte S, Lee T, Greenberg J, Shan B, Fan P, Ling Y, Medina JC, Houze J. Du X, et al. Among authors: shan b. Bioorg Med Chem Lett. 2011 Jun 15;21(12):3774-9. doi: 10.1016/j.bmcl.2011.04.053. Epub 2011 Apr 20. Bioorg Med Chem Lett. 2011. PMID: 21565497

3

Discovery and optimization of arylsulfonyl 3-(pyridin-2-yloxy)anilines as novel GPR119 agonists.

Zhang JK, Li AR, Yu M, Wang Y, Zhu J, Kayser F, Medina JC, Siegler K, Conn M, Shan B, Grillo MP, Eksterowicz J, Coward P, Liu JJ. Zhang JK, et al. Among authors: shan b. Bioorg Med Chem Lett. 2013 Jun 15;23(12):3609-13. doi: 10.1016/j.bmcl.2013.04.014. Epub 2013 Apr 15. Bioorg Med Chem Lett. 2013. PMID: 23648181

4

Discovery and optimization of N-(3-(1,3-dioxo-2,3-dihydro-1H-pyrrolo[3,4-c]pyridin-4-yloxy)phenyl)benzenesulfonamides as novel GPR119 agonists.

Yu M, Ken Zhang J, Wang Y, Zhu J, Kayser F, Medina JC, Siegler K, Conn M, Shan B, Grillo MP, Coward P, Jim Liu J. Yu M, et al. Among authors: shan b. Bioorg Med Chem Lett. 2014 Jan 1;24(1):156-60. doi: 10.1016/j.bmcl.2013.11.053. Epub 2013 Dec 1. Bioorg Med Chem Lett. 2014. PMID: 24332491

5

Discovery and optimization of 5-(2-((1-(phenylsulfonyl)-1,2,3,4-tetrahydroquinolin-7-yl)oxy)pyridin-4-yl)-1,2,4-oxadiazoles as novel gpr119 agonists.

Wang Y, Yu M, Zhu J, Zhang JK, Kayser F, Medina JC, Siegler K, Conn M, Shan B, Grillo MP, Liu JJ, Coward P. Wang Y, et al. Among authors: shan b. Bioorg Med Chem Lett. 2014 Feb 15;24(4):1133-7. doi: 10.1016/j.bmcl.2013.12.127. Epub 2014 Jan 8. Bioorg Med Chem Lett. 2014. PMID: 24440299

6

Novel antineoplastic agents with efficacy against multidrug resistant tumor cells.

Medina JC, Shan B, Beckmann H, Farrell RP, Clark DL, Learned RM, Roche D, Li A, Baichwal V, Case C, Baeuerle PA, Rosen T, Jaen JC. Medina JC, et al. Among authors: shan b. Bioorg Med Chem Lett. 1998 Oct 6;8(19):2653-6. doi: 10.1016/s0960-894x(98)00477-6. Bioorg Med Chem Lett. 1998. PMID: 9873597

7

Novel halogenated sulfonamides inhibit the growth of multidrug resistant MCF-7/ADR cancer cells.

Medina JC, Roche D, Shan B, Learned RM, Frankmoelle WP, Clark DL, Rosen T, Jaen JC. Medina JC, et al. Among authors: shan b. Bioorg Med Chem Lett. 1999 Jul 5;9(13):1843-6. doi: 10.1016/s0960-894x(99)00276-0. Bioorg Med Chem Lett. 1999. PMID: 10406652

8

Role of LXRs in control of lipogenesis.

Schultz JR, Tu H, Luk A, Repa JJ, Medina JC, Li L, Schwendner S, Wang S, Thoolen M, Mangelsdorf DJ, Lustig KD, Shan B. Schultz JR, et al. Among authors: shan b. Genes Dev. 2000 Nov 15;14(22):2831-8. doi: 10.1101/gad.850400. Genes Dev. 2000. PMID: 11090131 Free PMC article.

9

Glutathione S-transferase metabolism of the antineoplastic pentafluorophenylsulfonamide in tissue culture and mice.

Frankmoelle WP, Medina JC, Shan B, Narbut MR, Beckmann H. Frankmoelle WP, et al. Among authors: shan b. Drug Metab Dispos. 2000 Aug;28(8):951-8. Drug Metab Dispos. 2000. PMID: 10901706

10

Regulation of absorption and ABC1-mediated efflux of cholesterol by RXR heterodimers.

Repa JJ, Turley SD, Lobaccaro JA, Medina J, Li L, Lustig K, Shan B, Heyman RA, Dietschy JM, Mangelsdorf DJ. Repa JJ, et al. Among authors: shan b. Science. 2000 Sep 1;289(5484):1524-9. doi: 10.1126/science.289.5484.1524. Science. 2000. PMID: 10968783

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