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Transforming growth factor-beta2 suppresses collagen cleavage in cultured human osteoarthritic cartilage, reduces expression of genes associated with chondrocyte hypertrophy and degradation, and increases prostaglandin E(2) production.
Tchetina EV, Antoniou J, Tanzer M, Zukor DJ, Poole AR. Tchetina EV, et al. Among authors: zukor dj. Am J Pathol. 2006 Jan;168(1):131-40. doi: 10.2353/ajpath.2006.050369. Am J Pathol. 2006. PMID: 16400016 Free PMC article.
Selective enhancement of collagenase-mediated cleavage of resident type II collagen in cultured osteoarthritic cartilage and arrest with a synthetic inhibitor that spares collagenase 1 (matrix metalloproteinase 1).
Dahlberg L, Billinghurst RC, Manner P, Nelson F, Webb G, Ionescu M, Reiner A, Tanzer M, Zukor D, Chen J, van Wart HE, Poole AR. Dahlberg L, et al. Arthritis Rheum. 2000 Mar;43(3):673-82. doi: 10.1002/1529-0131(200003)43:3<673::AID-ANR25>3.0.CO;2-8. Arthritis Rheum. 2000. PMID: 10728762 Free article.
98 results