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Kaposi's sarcoma-associated herpesvirus induces the phosphatidylinositol 3-kinase-PKC-zeta-MEK-ERK signaling pathway in target cells early during infection: implications for infectivity.
Naranatt PP, Akula SM, Zien CA, Krishnan HH, Chandran B. Naranatt PP, et al. Among authors: chandran b. J Virol. 2003 Jan;77(2):1524-39. doi: 10.1128/jvi.77.2.1524-1539.2003. J Virol. 2003. PMID: 12502866 Free PMC article.
Human herpesvirus 8 (HHV-8) is implicated in the pathogenesis of Kaposi's sarcoma. HHV-8 envelope glycoprotein B (gB) possesses the RGD motif known to interact with integrin molecules, and HHV-8 infectivity was inhibited by RGD peptides, by antibodies against alpha3 and be …
Human herpesvirus 8 (HHV-8) is implicated in the pathogenesis of Kaposi's sarcoma. HHV-8 envelope glycoprotein B (gB) possesses the R …
Human herpesvirus 8 envelope glycoprotein B mediates cell adhesion via its RGD sequence.
Wang FZ, Akula SM, Sharma-Walia N, Zeng L, Chandran B. Wang FZ, et al. Among authors: chandran b. J Virol. 2003 Mar;77(5):3131-47. doi: 10.1128/jvi.77.5.3131-3147.2003. J Virol. 2003. PMID: 12584338 Free PMC article.
HHV-8 utilizes alpha3beta1 integrin as one of the receptors for its entry into the target cells via its gB interaction and induces the activation of focal adhesion kinase (FAK) (S. M. Akula, N. P. Pramod, F.-Z. Wang, and B. Chandran, Cell 108:407-419, 2002). Since F …
HHV-8 utilizes alpha3beta1 integrin as one of the receptors for its entry into the target cells via its gB interaction and induces the activ …
Kaposi's sarcoma-associated herpesvirus (human herpesvirus 8) infection of human fibroblast cells occurs through endocytosis.
Akula SM, Naranatt PP, Walia NS, Wang FZ, Fegley B, Chandran B. Akula SM, et al. Among authors: chandran b. J Virol. 2003 Jul;77(14):7978-90. doi: 10.1128/jvi.77.14.7978-7990.2003. J Virol. 2003. PMID: 12829837 Free PMC article.
Kaposi's sarcoma (KS)-associated herpesvirus or human herpesvirus 8 (HHV-8) DNA and transcripts have been detected in the B cells, macrophages, keratinocytes, and endothelial and epithelial cells of KS patients. ...HHV-8 also interacts with the alpha3beta1 integrin via its …
Kaposi's sarcoma (KS)-associated herpesvirus or human herpesvirus 8 (HHV-8) DNA and transcripts have been detected in the B cells, ma …
Concurrent expression of latent and a limited number of lytic genes with immune modulation and antiapoptotic function by Kaposi's sarcoma-associated herpesvirus early during infection of primary endothelial and fibroblast cells and subsequent decline of lytic gene expression.
Krishnan HH, Naranatt PP, Smith MS, Zeng L, Bloomer C, Chandran B. Krishnan HH, et al. Among authors: chandran b. J Virol. 2004 Apr;78(7):3601-20. doi: 10.1128/jvi.78.7.3601-3620.2004. J Virol. 2004. PMID: 15016882 Free PMC article.
Kaposi's sarcoma-associated herpesvirus/human herpesvirus 8 envelope glycoprotein gB induces the integrin-dependent focal adhesion kinase-Src-phosphatidylinositol 3-kinase-rho GTPase signal pathways and cytoskeletal rearrangements.
Sharma-Walia N, Naranatt PP, Krishnan HH, Zeng L, Chandran B. Sharma-Walia N, et al. Among authors: chandran b. J Virol. 2004 Apr;78(8):4207-23. doi: 10.1128/jvi.78.8.4207-4223.2004. J Virol. 2004. PMID: 15047836 Free PMC article.
Kaposi's sarcoma-associated herpesvirus modulates microtubule dynamics via RhoA-GTP-diaphanous 2 signaling and utilizes the dynein motors to deliver its DNA to the nucleus.
Naranatt PP, Krishnan HH, Smith MS, Chandran B. Naranatt PP, et al. Among authors: chandran b. J Virol. 2005 Jan;79(2):1191-206. doi: 10.1128/JVI.79.2.1191-1206.2005. J Virol. 2005. PMID: 15613346 Free PMC article.
M. Akula, C. A. Zien, H. H. Krishnan, and B. Chandran, J. Virol. 77:1524-1539, 2003). However, the mechanism by which the HHV-8-induced signaling pathway facilitates the complex events associated with the internalization and nuclear trafficking of internalized viral …
M. Akula, C. A. Zien, H. H. Krishnan, and B. Chandran, J. Virol. 77:1524-1539, 2003). However, the mechanism by which the HHV- …
Cyclooxygenase 2 induced by Kaposi's sarcoma-associated herpesvirus early during in vitro infection of target cells plays a role in the maintenance of latent viral gene expression.
Sharma-Walia N, Raghu H, Sadagopan S, Sivakumar R, Veettil MV, Naranatt PP, Smith MM, Chandran B. Sharma-Walia N, et al. Among authors: chandran b. J Virol. 2006 Jul;80(13):6534-52. doi: 10.1128/JVI.00231-06. J Virol. 2006. PMID: 16775340 Free PMC article.
R. Svojanovsky, C. Bloomer, S. Mathur, and B. Chandran, Cancer Res. 64:72-84, 2004). Since COX-2 is an important mediator of inflammatory and angiogenic responses, here, using real-time PCR, Western blot, and immunofluorescence assays, we characterized the COX-2 sti …
R. Svojanovsky, C. Bloomer, S. Mathur, and B. Chandran, Cancer Res. 64:72-84, 2004). Since COX-2 is an important mediator of i …
191 results