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The novel antioxidant, AC3056 (2,6-di-t-butyl-4-((dimethyl-4-methoxyphenylsilyl)methyloxy)phenol), reverses erectile dysfunction in diabetic rats and improves NO-mediated responses in penile tissue from diabetic men.
Angulo J, Peiró C, Cuevas P, Gabancho S, Fernández A, González-Corrochano R, La Fuente JM, Baron AD, Chen KS, de Tejada IS. Angulo J, et al. J Sex Med. 2009 Feb;6(2):373-87. doi: 10.1111/j.1743-6109.2008.01088.x. Epub 2008 Nov 18. J Sex Med. 2009. PMID: 19040617
Inhibition of vascular endothelial growth factor (VEGF)-induced endothelial proliferation, arterial relaxation, vascular permeability and angiogenesis by dobesilate.
Angulo J, Peiró C, Romacho T, Fernández A, Cuevas B, González-Corrochano R, Giménez-Gallego G, de Tejada IS, Sánchez-Ferrer CF, Cuevas P. Angulo J, et al. Among authors: gonzalez corrochano r. Eur J Pharmacol. 2011 Sep 30;667(1-3):153-9. doi: 10.1016/j.ejphar.2011.06.015. Epub 2011 Jun 22. Eur J Pharmacol. 2011. PMID: 21703259
Stimulation of large-conductance calcium-activated potassium channels inhibits neurogenic contraction of human bladder from patients with urinary symptoms and reverses acetic acid-induced bladder hyperactivity in rats.
La Fuente JM, Fernández A, Cuevas P, González-Corrochano R, Chen MX, Angulo J. La Fuente JM, et al. Among authors: gonzalez corrochano r. Eur J Pharmacol. 2014 Jul 15;735:68-76. doi: 10.1016/j.ejphar.2014.03.060. Epub 2014 Apr 18. Eur J Pharmacol. 2014. PMID: 24747752
Gentisic acid, a compound associated with plant defense and a metabolite of aspirin, heads a new class of in vivo fibroblast growth factor inhibitors.
Fernández IS, Cuevas P, Angulo J, López-Navajas P, Canales-Mayordomo A, González-Corrochano R, Lozano RM, Valverde S, Jiménez-Barbero J, Romero A, Giménez-Gallego G. Fernández IS, et al. Among authors: gonzalez corrochano r. J Biol Chem. 2010 Apr 9;285(15):11714-29. doi: 10.1074/jbc.M109.064618. Epub 2010 Feb 9. J Biol Chem. 2010. PMID: 20145243 Free PMC article.
14 results