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Genetic manipulation of polyamine catabolism in rodents.
Jänne J, Alhonen L, Pietilä M, Keinänen TA, Uimari A, Hyvönen MT, Pirinen E, Järvinen A. Jänne J, et al. Among authors: alhonen l. J Biochem. 2006 Feb;139(2):155-60. doi: 10.1093/jb/mvj035. J Biochem. 2006. PMID: 16452302 Review.
Targeted disruption of spermidine/spermine N1-acetyltransferase gene in mouse embryonic stem cells. Effects on polyamine homeostasis and sensitivity to polyamine analogues.
Niiranen K, Pietilä M, Pirttilä TJ, Järvinen A, Halmekytö M, Korhonen VP, Keinänen TA, Alhonen L, Jänne J. Niiranen K, et al. Among authors: alhonen l. J Biol Chem. 2002 Jul 12;277(28):25323-8. doi: 10.1074/jbc.M203599200. Epub 2002 May 8. J Biol Chem. 2002. PMID: 12000764 Free article.
Animal disease models generated by genetic engineering of polyamine metabolism.
Jänne J, Alhonen L, Keinänen TA, Pietilä M, Uimari A, Pirinen E, Hyvönen MT, Järvinen A. Jänne J, et al. Among authors: alhonen l. J Cell Mol Med. 2005 Oct-Dec;9(4):865-82. doi: 10.1111/j.1582-4934.2005.tb00385.x. J Cell Mol Med. 2005. PMID: 16364196 Free PMC article. Review.
activated polyamine catabolism in acute pancreatitis: alpha-methylated polyamine analogues prevent trypsinogen activation and pancreatitis-associated mortality.
Hyvönen MT, Herzig KH, Sinervirta R, Albrecht E, Nordback I, Sand J, Keinänen TA, Vepsäläinen J, Grigorenko N, Khomutov AR, Krüger B, Jänne J, Alhonen L. Hyvönen MT, et al. Among authors: alhonen l. Am J Pathol. 2006 Jan;168(1):115-22. doi: 10.2353/ajpath.2006.050518. Am J Pathol. 2006. PMID: 16400014 Free PMC article.
Mice with targeted disruption of spermidine/spermine N1-acetyltransferase gene maintain nearly normal tissue polyamine homeostasis but show signs of insulin resistance upon aging.
Niiranen K, Keinänen TA, Pirinen E, Heikkinen S, Tusa M, Fatrai S, Suppola S, Pietilä M, Uimari A, Laakso M, Alhonen L, Jänne J. Niiranen K, et al. Among authors: alhonen l. J Cell Mol Med. 2006 Oct-Dec;10(4):933-45. doi: 10.1111/j.1582-4934.2006.tb00536.x. J Cell Mol Med. 2006. PMID: 17125596 Free article.
177 results