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Page 1
Pharmacological and behavioral profile of N-(4-fluorophenylmethyl)-N-(1-methylpiperidin-4-yl)-N'-(4-(2-methylpropyloxy)phenylmethyl) carbamide (2R,3R)-dihydroxybutanedioate (2:1) (ACP-103), a novel 5-hydroxytryptamine(2A) receptor inverse agonist.
Vanover KE, Weiner DM, Makhay M, Veinbergs I, Gardell LR, Lameh J, Del Tredici AL, Piu F, Schiffer HH, Ott TR, Burstein ES, Uldam AK, Thygesen MB, Schlienger N, Andersson CM, Son TY, Harvey SC, Powell SB, Geyer MA, Tolf BR, Brann MR, Davis RE. Vanover KE, et al. Among authors: lameh j. J Pharmacol Exp Ther. 2006 May;317(2):910-8. doi: 10.1124/jpet.105.097006. Epub 2006 Feb 9. J Pharmacol Exp Ther. 2006. PMID: 16469866
Pharmacology of polymorphic variants of the human 5-HT1A receptor.
Del Tredici AL, Schiffer HH, Burstein ES, Lameh J, Mohell N, Hacksell U, Brann MR, Weiner DM. Del Tredici AL, et al. Among authors: lameh j. Biochem Pharmacol. 2004 Feb 1;67(3):479-90. doi: 10.1016/j.bcp.2003.09.030. Biochem Pharmacol. 2004. PMID: 15037200
Pharmacology of N-desmethylclozapine.
Lameh J, Burstein ES, Taylor E, Weiner DM, Vanover KE, Bonhaus DW. Lameh J, et al. Pharmacol Ther. 2007 Aug;115(2):223-31. doi: 10.1016/j.pharmthera.2007.05.004. Epub 2007 May 21. Pharmacol Ther. 2007. PMID: 17583355 Review.
Identification of novel selective V2 receptor non-peptide agonists.
Del Tredici AL, Vanover KE, Knapp AE, Bertozzi SM, Nash NR, Burstein ES, Lameh J, Currier EA, Davis RE, Brann MR, Mohell N, Olsson R, Piu F. Del Tredici AL, et al. Among authors: lameh j. Biochem Pharmacol. 2008 Oct 30;76(9):1134-41. doi: 10.1016/j.bcp.2008.08.004. Epub 2008 Aug 12. Biochem Pharmacol. 2008. PMID: 18761325
Identification and characterization of novel small-molecule protease-activated receptor 2 agonists.
Gardell LR, Ma JN, Seitzberg JG, Knapp AE, Schiffer HH, Tabatabaei A, Davis CN, Owens M, Clemons B, Wong KK, Lund B, Nash NR, Gao Y, Lameh J, Schmelzer K, Olsson R, Burstein ES. Gardell LR, et al. Among authors: lameh j. J Pharmacol Exp Ther. 2008 Dec;327(3):799-808. doi: 10.1124/jpet.108.142570. Epub 2008 Sep 3. J Pharmacol Exp Ther. 2008. PMID: 18768780
The role of M1 muscarinic receptor agonism of N-desmethylclozapine in the unique clinical effects of clozapine.
Weiner DM, Meltzer HY, Veinbergs I, Donohue EM, Spalding TA, Smith TT, Mohell N, Harvey SC, Lameh J, Nash N, Vanover KE, Olsson R, Jayathilake K, Lee M, Levey AI, Hacksell U, Burstein ES, Davis RE, Brann MR. Weiner DM, et al. Among authors: lameh j. Psychopharmacology (Berl). 2004 Dec;177(1-2):207-16. doi: 10.1007/s00213-004-1940-5. Epub 2004 Jul 16. Psychopharmacology (Berl). 2004. PMID: 15258717
Discovery of potential antipsychotic agents possessing pro-cognitive properties.
Lameh J, McFarland K, Ohlsson J, Ek F, Piu F, Burstein ES, Tabatabaei A, Olsson R, Bradley SR, Bonhaus DW. Lameh J, et al. Naunyn Schmiedebergs Arch Pharmacol. 2012 Mar;385(3):313-23. doi: 10.1007/s00210-011-0702-2. Epub 2011 Nov 15. Naunyn Schmiedebergs Arch Pharmacol. 2012. PMID: 22083558
AC-260584, an orally bioavailable M(1) muscarinic receptor allosteric agonist, improves cognitive performance in an animal model.
Bradley SR, Lameh J, Ohrmund L, Son T, Bajpai A, Nguyen D, Friberg M, Burstein ES, Spalding TA, Ott TR, Schiffer HH, Tabatabaei A, McFarland K, Davis RE, Bonhaus DW. Bradley SR, et al. Among authors: lameh j. Neuropharmacology. 2010 Feb;58(2):365-73. doi: 10.1016/j.neuropharm.2009.10.003. Epub 2009 Oct 14. Neuropharmacology. 2010. PMID: 19835892
50 results