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CD48-deficient mice have a pronounced defect in CD4(+) T cell activation.
González-Cabrero J, Wise CJ, Latchman Y, Freeman GJ, Sharpe AH, Reiser H. González-Cabrero J, et al. Among authors: sharpe ah. Proc Natl Acad Sci U S A. 1999 Feb 2;96(3):1019-23. doi: 10.1073/pnas.96.3.1019. Proc Natl Acad Sci U S A. 1999. PMID: 9927686 Free PMC article.
PD-L2 is a second ligand for PD-1 and inhibits T cell activation.
Latchman Y, Wood CR, Chernova T, Chaudhary D, Borde M, Chernova I, Iwai Y, Long AJ, Brown JA, Nunes R, Greenfield EA, Bourque K, Boussiotis VA, Carter LL, Carreno BM, Malenkovich N, Nishimura H, Okazaki T, Honjo T, Sharpe AH, Freeman GJ. Latchman Y, et al. Among authors: sharpe ah. Nat Immunol. 2001 Mar;2(3):261-8. doi: 10.1038/85330. Nat Immunol. 2001. PMID: 11224527
B7-dependent T-cell costimulation in mice lacking CD28 and CTLA4.
Mandelbrot DA, Oosterwegel MA, Shimizu K, Yamada A, Freeman GJ, Mitchell RN, Sayegh MH, Sharpe AH. Mandelbrot DA, et al. Among authors: sharpe ah. J Clin Invest. 2001 Apr;107(7):881-7. doi: 10.1172/JCI11710. J Clin Invest. 2001. PMID: 11285307 Free PMC article.
Negative co-receptors on lymphocytes.
Greenwald RJ, Latchman YE, Sharpe AH. Greenwald RJ, et al. Curr Opin Immunol. 2002 Jun;14(3):391-6. doi: 10.1016/s0952-7915(02)00341-2. Curr Opin Immunol. 2002. PMID: 11973140 Review.
846 results