Xu Z - Search Results

1

Activation of the apoptotic JNK pathway through the Rac1-binding scaffold protein POSH.

Xu Z, Greene LA. Xu Z, et al. Methods Enzymol. 2006;406:479-89. doi: 10.1016/S0076-6879(06)06036-8. Methods Enzymol. 2006. PMID: 16472680

2

beta-Amyloid-induced neuronal apoptosis requires c-Jun N-terminal kinase activation.

Troy CM, Rabacchi SA, Xu Z, Maroney AC, Connors TJ, Shelanski ML, Greene LA. Troy CM, et al. Among authors: xu z. J Neurochem. 2001 Apr;77(1):157-64. doi: 10.1046/j.1471-4159.2001.t01-1-00218.x. J Neurochem. 2001. PMID: 11279271 Free article.

3

Cep-1347 (KT7515), a semisynthetic inhibitor of the mixed lineage kinase family.

Maroney AC, Finn JP, Connors TJ, Durkin JT, Angeles T, Gessner G, Xu Z, Meyer SL, Savage MJ, Greene LA, Scott RW, Vaught JL. Maroney AC, et al. Among authors: xu z. J Biol Chem. 2001 Jul 6;276(27):25302-8. doi: 10.1074/jbc.M011601200. Epub 2001 Apr 26. J Biol Chem. 2001. PMID: 11325962 Free article.

4

The MLK family mediates c-Jun N-terminal kinase activation in neuronal apoptosis.

Xu Z, Maroney AC, Dobrzanski P, Kukekov NV, Greene LA. Xu Z, et al. Mol Cell Biol. 2001 Jul;21(14):4713-24. doi: 10.1128/MCB.21.14.4713-4724.2001. Mol Cell Biol. 2001. PMID: 11416147 Free PMC article.

5

POSH acts as a scaffold for a multiprotein complex that mediates JNK activation in apoptosis.

Xu Z, Kukekov NV, Greene LA. Xu Z, et al. EMBO J. 2003 Jan 15;22(2):252-61. doi: 10.1093/emboj/cdg021. EMBO J. 2003. PMID: 12514131 Free PMC article.

6

Siah1 interacts with the scaffold protein POSH to promote JNK activation and apoptosis.

Xu Z, Sproul A, Wang W, Kukekov N, Greene LA. Xu Z, et al. J Biol Chem. 2006 Jan 6;281(1):303-12. doi: 10.1074/jbc.M509060200. Epub 2005 Oct 17. J Biol Chem. 2006. PMID: 16230351 Free article.

7

Regulation of apoptotic c-Jun N-terminal kinase signaling by a stabilization-based feed-forward loop.

Xu Z, Kukekov NV, Greene LA. Xu Z, et al. Mol Cell Biol. 2005 Nov;25(22):9949-59. doi: 10.1128/MCB.25.22.9949-9959.2005. Mol Cell Biol. 2005. PMID: 16260609 Free PMC article.

8

Direct interaction of the molecular scaffolds POSH and JIP is required for apoptotic activation of JNKs.

Kukekov NV, Xu Z, Greene LA. Kukekov NV, et al. Among authors: xu z. J Biol Chem. 2006 Jun 2;281(22):15517-24. doi: 10.1074/jbc.M601056200. Epub 2006 Mar 29. J Biol Chem. 2006. PMID: 16571722 Free article.

9

Proapoptotic Nix activates the JNK pathway by interacting with POSH and mediates death in a Parkinson disease model.

Wilhelm M, Xu Z, Kukekov NV, Gire S, Greene LA. Wilhelm M, et al. Among authors: xu z. J Biol Chem. 2007 Jan 12;282(2):1288-95. doi: 10.1074/jbc.M607038200. Epub 2006 Nov 9. J Biol Chem. 2007. PMID: 17095503 Free article.

10

JNK pathway: diseases and therapeutic potential.

Cui J, Zhang M, Zhang YQ, Xu ZH. Cui J, et al. Acta Pharmacol Sin. 2007 May;28(5):601-8. doi: 10.1111/j.1745-7254.2007.00579.x. Acta Pharmacol Sin. 2007. PMID: 17439715 Review.

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