Sarkari F - Search Results

1

Molecular recognition of p53 and MDM2 by USP7/HAUSP.

Sheng Y, Saridakis V, Sarkari F, Duan S, Wu T, Arrowsmith CH, Frappier L. Sheng Y, et al. Among authors: sarkari f. Nat Struct Mol Biol. 2006 Mar;13(3):285-91. doi: 10.1038/nsmb1067. Epub 2006 Feb 12. Nat Struct Mol Biol. 2006. PMID: 16474402

2

Structure of the p53 binding domain of HAUSP/USP7 bound to Epstein-Barr nuclear antigen 1 implications for EBV-mediated immortalization.

Saridakis V, Sheng Y, Sarkari F, Holowaty MN, Shire K, Nguyen T, Zhang RG, Liao J, Lee W, Edwards AM, Arrowsmith CH, Frappier L. Saridakis V, et al. Among authors: sarkari f. Mol Cell. 2005 Apr 1;18(1):25-36. doi: 10.1016/j.molcel.2005.02.029. Mol Cell. 2005. PMID: 15808506 Free article.

3

Further insight into substrate recognition by USP7: structural and biochemical analysis of the HdmX and Hdm2 interactions with USP7.

Sarkari F, La Delfa A, Arrowsmith CH, Frappier L, Sheng Y, Saridakis V. Sarkari F, et al. J Mol Biol. 2010 Oct 8;402(5):825-37. doi: 10.1016/j.jmb.2010.08.017. Epub 2010 Aug 14. J Mol Biol. 2010. PMID: 20713061

4

USP7/HAUSP promotes the sequence-specific DNA binding activity of p53.

Sarkari F, Sheng Y, Frappier L. Sarkari F, et al. PLoS One. 2010 Sep 27;5(9):e13040. doi: 10.1371/journal.pone.0013040. PLoS One. 2010. PMID: 20885946 Free PMC article.

5

The herpesvirus associated ubiquitin specific protease, USP7, is a negative regulator of PML proteins and PML nuclear bodies.

Sarkari F, Wang X, Nguyen T, Frappier L. Sarkari F, et al. PLoS One. 2011 Jan 31;6(1):e16598. doi: 10.1371/journal.pone.0016598. PLoS One. 2011. PMID: 21305000 Free PMC article.

6

Ubiquitin-specific protease 7 is a regulator of ubiquitin-conjugating enzyme UbE2E1.

Sarkari F, Wheaton K, La Delfa A, Mohamed M, Shaikh F, Khatun R, Arrowsmith CH, Frappier L, Saridakis V, Sheng Y. Sarkari F, et al. J Biol Chem. 2013 Jun 7;288(23):16975-16985. doi: 10.1074/jbc.M113.469262. Epub 2013 Apr 19. J Biol Chem. 2013. PMID: 23603909 Free PMC article.

7

Epstein-Barr nuclear antigen 1 contributes to nasopharyngeal carcinoma through disruption of PML nuclear bodies.

Sivachandran N, Sarkari F, Frappier L. Sivachandran N, et al. Among authors: sarkari f. PLoS Pathog. 2008 Oct 3;4(10):e1000170. doi: 10.1371/journal.ppat.1000170. PLoS Pathog. 2008. PMID: 18833293 Free PMC article.

8

EBNA1-mediated recruitment of a histone H2B deubiquitylating complex to the Epstein-Barr virus latent origin of DNA replication.

Sarkari F, Sanchez-Alcaraz T, Wang S, Holowaty MN, Sheng Y, Frappier L. Sarkari F, et al. PLoS Pathog. 2009 Oct;5(10):e1000624. doi: 10.1371/journal.ppat.1000624. Epub 2009 Oct 16. PLoS Pathog. 2009. PMID: 19834552 Free PMC article.

9

UbE2E1/UBCH6 Is a Critical in Vivo E2 for the PRC1-catalyzed Ubiquitination of H2A at Lys-119.

Wheaton K, Sarkari F, Stanly Johns B, Davarinejad H, Egorova O, Kaustov L, Raught B, Saridakis V, Sheng Y. Wheaton K, et al. Among authors: sarkari f. J Biol Chem. 2017 Feb 17;292(7):2893-2902. doi: 10.1074/jbc.M116.749564. Epub 2017 Jan 10. J Biol Chem. 2017. PMID: 28073915 Free PMC article.

10

Discovery of ERD-1233 as a Potent and Orally Efficacious Estrogen Receptor PROTAC Degrader for the Treatment of ER+ Human Breast Cancer.

Acharyya RK, Rej RK, Hu B, Chen Z, Wu D, Lu J, Metwally H, McEachern D, Wang Y, Jiang W, Bai L, Tošović J, Gersch CL, Xu G, Zhang W, Wu W, Priestley ES, Sui Z, Sarkari F, Wen B, Sun D, Rae JM, Wang S. Acharyya RK, et al. Among authors: sarkari f. J Med Chem. 2024 Nov 14;67(21):19010-19037. doi: 10.1021/acs.jmedchem.4c01521. Epub 2024 Nov 1. J Med Chem. 2024. PMID: 39485242

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