Eldredge J - Search Results

1

Formation of virus-like clusters is an intrinsic property of the tumor necrosis factor family member BAFF (B cell activating factor).

Cachero TG, Schwartz IM, Qian F, Day ES, Bossen C, Ingold K, Tardivel A, Krushinskie D, Eldredge J, Silvian L, Lugovskoy A, Farrington GK, Strauch K, Schneider P, Whitty A. Cachero TG, et al. Among authors: eldredge j. Biochemistry. 2006 Feb 21;45(7):2006-13. doi: 10.1021/bi051685o. Biochemistry. 2006. PMID: 16475789

2

Stoichiometry of LTbetaR binding to LIGHT.

Eldredge J, Berkowitz S, Corin AF, Day ES, Hayes D, Meier W, Strauch K, Zafari M, Tadi M, Farrington GK. Eldredge J, et al. Biochemistry. 2006 Aug 22;45(33):10117-28. doi: 10.1021/bi060210+. Biochemistry. 2006. PMID: 16906770

3

Improving the solubility of anti-LINGO-1 monoclonal antibody Li33 by isotype switching and targeted mutagenesis.

Pepinsky RB, Silvian L, Berkowitz SA, Farrington G, Lugovskoy A, Walus L, Eldredge J, Capili A, Mi S, Graff C, Garber E. Pepinsky RB, et al. Among authors: eldredge j. Protein Sci. 2010 May;19(5):954-66. doi: 10.1002/pro.372. Protein Sci. 2010. PMID: 20198683 Free PMC article.

4

Small-molecule inhibition of TNF-alpha.

He MM, Smith AS, Oslob JD, Flanagan WM, Braisted AC, Whitty A, Cancilla MT, Wang J, Lugovskoy AA, Yoburn JC, Fung AD, Farrington G, Eldredge JK, Day ES, Cruz LA, Cachero TG, Miller SK, Friedman JE, Choong IC, Cunningham BC. He MM, et al. Among authors: eldredge jk. Science. 2005 Nov 11;310(5750):1022-5. doi: 10.1126/science.1116304. Science. 2005. PMID: 16284179

5

An antibody loop replacement design feasibility study and a loop-swapped dimer structure.

Clark LA, Boriack-Sjodin PA, Day E, Eldredge J, Fitch C, Jarpe M, Miller S, Li Y, Simon K, van Vlijmen HW. Clark LA, et al. Among authors: eldredge j. Protein Eng Des Sel. 2009 Feb;22(2):93-101. doi: 10.1093/protein/gzn072. Epub 2008 Dec 10. Protein Eng Des Sel. 2009. PMID: 19074157

6

A novel platform for engineering blood-brain barrier-crossing bispecific biologics.

Farrington GK, Caram-Salas N, Haqqani AS, Brunette E, Eldredge J, Pepinsky B, Antognetti G, Baumann E, Ding W, Garber E, Jiang S, Delaney C, Boileau E, Sisk WP, Stanimirovic DB. Farrington GK, et al. Among authors: eldredge j. FASEB J. 2014 Nov;28(11):4764-78. doi: 10.1096/fj.14-253369. Epub 2014 Jul 28. FASEB J. 2014. PMID: 25070367

7

Endosomal trafficking regulates receptor-mediated transcytosis of antibodies across the blood brain barrier.

Haqqani AS, Delaney CE, Brunette E, Baumann E, Farrington GK, Sisk W, Eldredge J, Ding W, Tremblay TL, Stanimirovic DB. Haqqani AS, et al. Among authors: eldredge j. J Cereb Blood Flow Metab. 2018 Apr;38(4):727-740. doi: 10.1177/0271678X17740031. Epub 2017 Nov 15. J Cereb Blood Flow Metab. 2018. PMID: 29140158 Free PMC article.

8

Affinity enhancement of an in vivo matured therapeutic antibody using structure-based computational design.

Clark LA, Boriack-Sjodin PA, Eldredge J, Fitch C, Friedman B, Hanf KJ, Jarpe M, Liparoto SF, Li Y, Lugovskoy A, Miller S, Rushe M, Sherman W, Simon K, Van Vlijmen H. Clark LA, et al. Among authors: eldredge j. Protein Sci. 2006 May;15(5):949-60. doi: 10.1110/ps.052030506. Epub 2006 Apr 5. Protein Sci. 2006. PMID: 16597831 Free PMC article.

9

Influence of canonical structure determining residues on antibody affinity and stability.

Clark LA, Demarest SJ, Eldredge J, Jarpe MB, Li Y, Simon K, van Vlijmen HW. Clark LA, et al. Among authors: eldredge j. J Struct Biol. 2014 Feb;185(2):223-7. doi: 10.1016/j.jsb.2013.08.009. Epub 2013 Aug 29. J Struct Biol. 2014. PMID: 23994046

10

Nucleic acid hybridization assays employing dA-tailed capture probes. I. Multiple capture methods.

Morrissey DV, Lombardo M, Eldredge JK, Kearney KR, Groody EP, Collins ML. Morrissey DV, et al. Among authors: eldredge jk. Anal Biochem. 1989 Sep;181(2):345-59. doi: 10.1016/0003-2697(89)90255-8. Anal Biochem. 1989. PMID: 2510553

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