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CSPalpha-deficiency causes massive and rapid photoreceptor degeneration.
Schmitz F, Tabares L, Khimich D, Strenzke N, de la Villa-Polo P, Castellano-Muñoz M, Bulankina A, Moser T, Fernández-Chacón R, Südhof TC. Schmitz F, et al. Among authors: sudhof tc. Proc Natl Acad Sci U S A. 2006 Feb 21;103(8):2926-31. doi: 10.1073/pnas.0510060103. Epub 2006 Feb 13. Proc Natl Acad Sci U S A. 2006. PMID: 16477021 Free PMC article.
The synaptic vesicle protein CSP alpha prevents presynaptic degeneration.
Fernández-Chacón R, Wölfel M, Nishimune H, Tabares L, Schmitz F, Castellano-Muñoz M, Rosenmund C, Montesinos ML, Sanes JR, Schneggenburger R, Südhof TC. Fernández-Chacón R, et al. Among authors: sudhof tc. Neuron. 2004 Apr 22;42(2):237-51. doi: 10.1016/s0896-6273(04)00190-4. Neuron. 2004. PMID: 15091340 Free article.
Deletion of CASK in mice is lethal and impairs synaptic function.
Atasoy D, Schoch S, Ho A, Nadasy KA, Liu X, Zhang W, Mukherjee K, Nosyreva ED, Fernandez-Chacon R, Missler M, Kavalali ET, Südhof TC. Atasoy D, et al. Among authors: sudhof tc. Proc Natl Acad Sci U S A. 2007 Feb 13;104(7):2525-30. doi: 10.1073/pnas.0611003104. Epub 2007 Feb 7. Proc Natl Acad Sci U S A. 2007. PMID: 17287346 Free PMC article.
671 results