Jeganathan KB - Search Results

1

Securin associates with APCCdh1 in prometaphase but its destruction is delayed by Rae1 and Nup98 until the metaphase/anaphase transition.

Jeganathan KB, Baker DJ, van Deursen JM. Jeganathan KB, et al. Cell Cycle. 2006 Feb;5(4):366-70. doi: 10.4161/cc.5.4.2483. Epub 2006 Feb 15. Cell Cycle. 2006. PMID: 16479161

2

Rae1 is an essential mitotic checkpoint regulator that cooperates with Bub3 to prevent chromosome missegregation.

Babu JR, Jeganathan KB, Baker DJ, Wu X, Kang-Decker N, van Deursen JM. Babu JR, et al. Among authors: jeganathan kb. J Cell Biol. 2003 Feb 3;160(3):341-53. doi: 10.1083/jcb.200211048. Epub 2003 Jan 27. J Cell Biol. 2003. PMID: 12551952 Free PMC article.

3

BubR1 insufficiency causes early onset of aging-associated phenotypes and infertility in mice.

Baker DJ, Jeganathan KB, Cameron JD, Thompson M, Juneja S, Kopecka A, Kumar R, Jenkins RB, de Groen PC, Roche P, van Deursen JM. Baker DJ, et al. Among authors: jeganathan kb. Nat Genet. 2004 Jul;36(7):744-9. doi: 10.1038/ng1382. Epub 2004 Jun 20. Nat Genet. 2004. PMID: 15208629

4

The Rae1-Nup98 complex prevents aneuploidy by inhibiting securin degradation.

Jeganathan KB, Malureanu L, van Deursen JM. Jeganathan KB, et al. Nature. 2005 Dec 15;438(7070):1036-9. doi: 10.1038/nature04221. Nature. 2005. PMID: 16355229

5

Early aging-associated phenotypes in Bub3/Rae1 haploinsufficient mice.

Baker DJ, Jeganathan KB, Malureanu L, Perez-Terzic C, Terzic A, van Deursen JM. Baker DJ, et al. Among authors: jeganathan kb. J Cell Biol. 2006 Feb 13;172(4):529-40. doi: 10.1083/jcb.200507081. J Cell Biol. 2006. PMID: 16476774 Free PMC article.

6

Differential mitotic checkpoint protein requirements in somatic and germ cells.

Jeganathan KB, van Deursen JM. Jeganathan KB, et al. Biochem Soc Trans. 2006 Aug;34(Pt 4):583-6. doi: 10.1042/BST0340583. Biochem Soc Trans. 2006. PMID: 16856867

7

Bub1 mediates cell death in response to chromosome missegregation and acts to suppress spontaneous tumorigenesis.

Jeganathan K, Malureanu L, Baker DJ, Abraham SC, van Deursen JM. Jeganathan K, et al. J Cell Biol. 2007 Oct 22;179(2):255-67. doi: 10.1083/jcb.200706015. Epub 2007 Oct 15. J Cell Biol. 2007. PMID: 17938250 Free PMC article.

8

Resolution of sister centromeres requires RanBP2-mediated SUMOylation of topoisomerase IIalpha.

Dawlaty MM, Malureanu L, Jeganathan KB, Kao E, Sustmann C, Tahk S, Shuai K, Grosschedl R, van Deursen JM. Dawlaty MM, et al. Among authors: jeganathan kb. Cell. 2008 Apr 4;133(1):103-15. doi: 10.1016/j.cell.2008.01.045. Cell. 2008. PMID: 18394993 Free PMC article.

9

Opposing roles for p16Ink4a and p19Arf in senescence and ageing caused by BubR1 insufficiency.

Baker DJ, Perez-Terzic C, Jin F, Pitel KS, Niederländer NJ, Jeganathan K, Yamada S, Reyes S, Rowe L, Hiddinga HJ, Eberhardt NL, Terzic A, van Deursen JM. Baker DJ, et al. Nat Cell Biol. 2008 Jul;10(7):825-36. doi: 10.1038/ncb1744. Epub 2008 May 30. Nat Cell Biol. 2008. PMID: 18516091 Free PMC article.

10

BubR1 N terminus acts as a soluble inhibitor of cyclin B degradation by APC/C(Cdc20) in interphase.

Malureanu LA, Jeganathan KB, Hamada M, Wasilewski L, Davenport J, van Deursen JM. Malureanu LA, et al. Among authors: jeganathan kb. Dev Cell. 2009 Jan;16(1):118-31. doi: 10.1016/j.devcel.2008.11.004. Dev Cell. 2009. PMID: 19154723 Free PMC article.

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