Gazdar AF - Search Results

1

Multiple oncogenic changes (K-RAS(V12), p53 knockdown, mutant EGFRs, p16 bypass, telomerase) are not sufficient to confer a full malignant phenotype on human bronchial epithelial cells.

Sato M, Vaughan MB, Girard L, Peyton M, Lee W, Shames DS, Ramirez RD, Sunaga N, Gazdar AF, Shay JW, Minna JD. Sato M, et al. Among authors: gazdar af. Cancer Res. 2006 Feb 15;66(4):2116-28. doi: 10.1158/0008-5472.CAN-05-2521. Cancer Res. 2006. PMID: 16489012

2

RNA interference-mediated knockdown of DNA methyltransferase 1 leads to promoter demethylation and gene re-expression in human lung and breast cancer cells.

Suzuki M, Sunaga N, Shames DS, Toyooka S, Gazdar AF, Minna JD. Suzuki M, et al. Among authors: gazdar af. Cancer Res. 2004 May 1;64(9):3137-43. doi: 10.1158/0008-5472.can-03-3046. Cancer Res. 2004. PMID: 15126351

3

Different roles for caveolin-1 in the development of non-small cell lung cancer versus small cell lung cancer.

Sunaga N, Miyajima K, Suzuki M, Sato M, White MA, Ramirez RD, Shay JW, Gazdar AF, Minna JD. Sunaga N, et al. Among authors: gazdar af. Cancer Res. 2004 Jun 15;64(12):4277-85. doi: 10.1158/0008-5472.CAN-03-3941. Cancer Res. 2004. PMID: 15205342

4

Immortalization of human bronchial epithelial cells in the absence of viral oncoproteins.

Ramirez RD, Sheridan S, Girard L, Sato M, Kim Y, Pollack J, Peyton M, Zou Y, Kurie JM, Dimaio JM, Milchgrub S, Smith AL, Souza RF, Gilbey L, Zhang X, Gandia K, Vaughan MB, Wright WE, Gazdar AF, Shay JW, Minna JD. Ramirez RD, et al. Among authors: gazdar af. Cancer Res. 2004 Dec 15;64(24):9027-34. doi: 10.1158/0008-5472.CAN-04-3703. Cancer Res. 2004. PMID: 15604268

5

Somatic mutations of the HER2 kinase domain in lung adenocarcinomas.

Shigematsu H, Takahashi T, Nomura M, Majmudar K, Suzuki M, Lee H, Wistuba II, Fong KM, Toyooka S, Shimizu N, Fujisawa T, Minna JD, Gazdar AF. Shigematsu H, et al. Among authors: gazdar af. Cancer Res. 2005 Mar 1;65(5):1642-6. doi: 10.1158/0008-5472.CAN-04-4235. Cancer Res. 2005. PMID: 15753357

6

EGFR tyrosine kinase domain mutations are detected in histologically normal respiratory epithelium in lung cancer patients.

Tang X, Shigematsu H, Bekele BN, Roth JA, Minna JD, Hong WK, Gazdar AF, Wistuba II. Tang X, et al. Among authors: gazdar af. Cancer Res. 2005 Sep 1;65(17):7568-72. doi: 10.1158/0008-5472.CAN-05-1705. Cancer Res. 2005. PMID: 16140919

7

Inhibition of EGFR signaling: all mutations are not created equal.

Gazdar AF, Minna JD. Gazdar AF, et al. PLoS Med. 2005 Nov;2(11):e377. doi: 10.1371/journal.pmed.0020377. Epub 2005 Nov 29. PLoS Med. 2005. PMID: 16288556 Free PMC article.

8

Non-small-cell lung cancers with kinase domain mutations in the epidermal growth factor receptor are sensitive to ionizing radiation.

Das AK, Sato M, Story MD, Peyton M, Graves R, Redpath S, Girard L, Gazdar AF, Shay JW, Minna JD, Nirodi CS. Das AK, et al. Among authors: gazdar af. Cancer Res. 2006 Oct 1;66(19):9601-8. doi: 10.1158/0008-5472.CAN-06-2627. Cancer Res. 2006. PMID: 17018617

9

A translational view of the molecular pathogenesis of lung cancer.

Sato M, Shames DS, Gazdar AF, Minna JD. Sato M, et al. Among authors: gazdar af. J Thorac Oncol. 2007 Apr;2(4):327-43. doi: 10.1097/01.JTO.0000263718.69320.4c. J Thorac Oncol. 2007. PMID: 17409807 Free article. Review.

10

Epidermal growth factor receptors with tyrosine kinase domain mutations exhibit reduced Cbl association, poor ubiquitylation, and down-regulation but are efficiently internalized.

Padrón D, Sato M, Shay JW, Gazdar AF, Minna JD, Roth MG. Padrón D, et al. Among authors: gazdar af. Cancer Res. 2007 Aug 15;67(16):7695-702. doi: 10.1158/0008-5472.CAN-07-0484. Cancer Res. 2007. PMID: 17699773 Free PMC article.

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