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143 results

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Page 1
Human antibodies for immunotherapy development generated via a human B cell hybridoma technology.
Li J, Sai T, Berger M, Chao Q, Davidson D, Deshmukh G, Drozdowski B, Ebel W, Harley S, Henry M, Jacob S, Kline B, Lazo E, Rotella F, Routhier E, Rudolph K, Sage J, Simon P, Yao J, Zhou Y, Kavuru M, Bonfield T, Thomassen MJ, Sass PM, Nicolaides NC, Grasso L. Li J, et al. Among authors: chao q. Proc Natl Acad Sci U S A. 2006 Mar 7;103(10):3557-62. doi: 10.1073/pnas.0511285103. Epub 2006 Feb 27. Proc Natl Acad Sci U S A. 2006. PMID: 16505368 Free PMC article.
Morphogenics as a tool for target discovery and drug development.
Nicolaides NC, Ebel W, Kline B, Chao Q, Routhier E, Sass PM, Grasso L. Nicolaides NC, et al. Among authors: chao q. Ann N Y Acad Sci. 2005 Nov;1059:86-96. doi: 10.1196/annals.1339.029. Ann N Y Acad Sci. 2005. PMID: 16382047 Review.
Generation and characterization of high affinity human monoclonal antibodies that neutralize staphylococcal enterotoxin B.
Drozdowski B, Zhou Y, Kline B, Spidel J, Chan YY, Albone E, Turchin H, Chao Q, Henry M, Balogach J, Routhier E, Bavari S, Nicolaides NC, Sass PM, Grasso L. Drozdowski B, et al. Among authors: chao q. J Immune Based Ther Vaccines. 2010 Dec 21;8:9. doi: 10.1186/1476-8518-8-9. J Immune Based Ther Vaccines. 2010. PMID: 21176153 Free PMC article.
Developing novel biopharmaceutical products through morphogenics.
Nicolaides NC, Sass PM, Chao Q, Kline JB, Ebel W, Routhier E, Zhou Y, Grasso L. Nicolaides NC, et al. Among authors: chao q. Expert Opin Drug Discov. 2007 Dec;2(12):1619-29. doi: 10.1517/17460441.2.12.1619. Expert Opin Drug Discov. 2007. PMID: 23488905
The antitumor activity of the human FOLR1-specific monoclonal antibody, farletuzumab, in an ovarian cancer mouse model is mediated by antibody-dependent cellular cytotoxicity.
Lin J, Spidel JL, Maddage CJ, Rybinski KA, Kennedy RP, Krauthauser CL, Park YC, Albone EF, Jacob S, Goserud MT, Martinez BP, Chao Q, Zhou Y, Nicolaides NC, Kline JB, Grasso L. Lin J, et al. Among authors: chao q. Cancer Biol Ther. 2013 Nov;14(11):1032-8. doi: 10.4161/cbt.26106. Epub 2013 Aug 28. Cancer Biol Ther. 2013. PMID: 24025360 Free PMC article.
Targeting endosialin/CD248 through antibody-mediated internalization results in impaired pericyte maturation and dysfunctional tumor microvasculature.
Rybinski K, Imtiyaz HZ, Mittica B, Drozdowski B, Fulmer J, Furuuchi K, Fernando S, Henry M, Chao Q, Kline B, Albone E, Wustner J, Lin J, Nicolaides NC, Grasso L, Zhou Y. Rybinski K, et al. Among authors: chao q. Oncotarget. 2015 Sep 22;6(28):25429-40. doi: 10.18632/oncotarget.4559. Oncotarget. 2015. PMID: 26327620 Free PMC article.
Tumor antigen CA125 suppresses antibody-dependent cellular cytotoxicity (ADCC) via direct antibody binding and suppressed Fc-γ receptor engagement.
Kline JB, Kennedy RP, Albone E, Chao Q, Fernando S, McDonough JM, Rybinski K, Wang W, Somers EB, Schweizer C, Grasso L, Nicolaides NC. Kline JB, et al. Among authors: chao q. Oncotarget. 2017 Jul 7;8(32):52045-52060. doi: 10.18632/oncotarget.19090. eCollection 2017 Aug 8. Oncotarget. 2017. PMID: 28881712 Free PMC article.
143 results