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Human antibodies for immunotherapy development generated via a human B cell hybridoma technology.
Li J, Sai T, Berger M, Chao Q, Davidson D, Deshmukh G, Drozdowski B, Ebel W, Harley S, Henry M, Jacob S, Kline B, Lazo E, Rotella F, Routhier E, Rudolph K, Sage J, Simon P, Yao J, Zhou Y, Kavuru M, Bonfield T, Thomassen MJ, Sass PM, Nicolaides NC, Grasso L. Li J, et al. Among authors: jacob s. Proc Natl Acad Sci U S A. 2006 Mar 7;103(10):3557-62. doi: 10.1073/pnas.0511285103. Epub 2006 Feb 27. Proc Natl Acad Sci U S A. 2006. PMID: 16505368 Free PMC article.
The antitumor activity of the human FOLR1-specific monoclonal antibody, farletuzumab, in an ovarian cancer mouse model is mediated by antibody-dependent cellular cytotoxicity.
Lin J, Spidel JL, Maddage CJ, Rybinski KA, Kennedy RP, Krauthauser CL, Park YC, Albone EF, Jacob S, Goserud MT, Martinez BP, Chao Q, Zhou Y, Nicolaides NC, Kline JB, Grasso L. Lin J, et al. Among authors: jacob s. Cancer Biol Ther. 2013 Nov;14(11):1032-8. doi: 10.4161/cbt.26106. Epub 2013 Aug 28. Cancer Biol Ther. 2013. PMID: 24025360 Free PMC article.
Generation of therapeutic immunoconjugates via Residue-Specific Conjugation Technology (RESPECT) utilizing a native cysteine in the light chain framework of Oryctolagus cuniculus.
Albone EF, Spidel JL, Cheng X, Park YC, Jacob S, Milinichik AZ, Vaessen B, Butler J, Kline JB, Grasso L. Albone EF, et al. Among authors: jacob s. Cancer Biol Ther. 2017 May 4;18(5):347-357. doi: 10.1080/15384047.2017.1312232. Epub 2017 Apr 10. Cancer Biol Ther. 2017. PMID: 28394698 Free PMC article.
Efgartigimod efficacy and safety in refractory myasthenia gravis: UK's first real-world experience.
Moniz Dionísio J, Ambrose P, Burke G, Farrugia ME, Garcia-Reitboeck P, Hewamadduma C, Hill M, Howard RS, Jacob S, Kullmann D, Leite MI, Miller J, Pinto A, Pritchard J, Riswick T, Sathasivam S, Thambirajah N, Viegas S, Norwood F, Spillane J. Moniz Dionísio J, et al. Among authors: jacob s. J Neurol Neurosurg Psychiatry. 2025 Jan 11:jnnp-2024-334086. doi: 10.1136/jnnp-2024-334086. Online ahead of print. J Neurol Neurosurg Psychiatry. 2025. PMID: 39798959
2,670 results