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Oncogenic PKA signaling increases c-MYC protein expression through multiple targetable mechanisms.
Chan GKL, Maisel S, Hwang YC, Pascual BC, Wolber RRB, Vu P, Patra KC, Bouhaddou M, Kenerson HL, Lim HC, Long D, Yeung RS, Sethupathy P, Swaney DL, Krogan NJ, Turnham RE, Riehle KJ, Scott JD, Bardeesy N, Gordan JD. Chan GKL, et al. Among authors: gordan jd. Elife. 2023 Jan 24;12:e69521. doi: 10.7554/eLife.69521. Elife. 2023. PMID: 36692000 Free PMC article.
DNAJB1-PRKACA fusion protein-regulated LINC00473 promotes tumor growth and alters mitochondrial fitness in fibrolamellar carcinoma.
Ma RK, Tsai PY, Farghli AR, Shumway A, Kanke M, Gordan JD, Gujral TS, Vakili K, Nukaya M, Noetzli L, Ronnekleiv-Kelly S, Broom W, Barrow J, Sethupathy P. Ma RK, et al. Among authors: gordan jd. PLoS Genet. 2024 Mar 21;20(3):e1011216. doi: 10.1371/journal.pgen.1011216. eCollection 2024 Mar. PLoS Genet. 2024. PMID: 38512964 Free PMC article.
Protein kinase A and local signaling in cancer.
Rosenthal KJ, Gordan JD, Scott JD. Rosenthal KJ, et al. Among authors: gordan jd. Biochem J. 2024 Nov 20;481(22):1659-1677. doi: 10.1042/BCJ20230352. Biochem J. 2024. PMID: 39540434 Review.
DNAJB1-PRKACA fusion drives fibrolamellar liver cancer through impaired SIK signaling and CRTC2/p300-mediated transcriptional reprogramming.
Gritti I, Wan J, Weeresekara V, Vaz JM, Tarantino G, Bryde TH, Vijay V, Kammula AV, Kattel P, Zhu S, Vu P, Chan M, Wu MJ, Gordan JD, Patra KC, Silveira VS, Manguso RT, Wein MN, Ott CJ, Qi J, Liu D, Sakamoto K, Gujral TS, Bardeesy N. Gritti I, et al. Among authors: gordan jd. Cancer Discov. 2024 Sep 27. doi: 10.1158/2159-8290.CD-24-0634. Online ahead of print. Cancer Discov. 2024. PMID: 39326063
Systemic Therapy for Advanced Hepatocellular Carcinoma: ASCO Guideline Update.
Gordan JD, Kennedy EB, Abou-Alfa GK, Beal E, Finn RS, Gade TP, Goff L, Gupta S, Guy J, Hoang HT, Iyer R, Jaiyesimi I, Jhawer M, Karippot A, Kaseb AO, Kelley RK, Kortmansky J, Leaf A, Remak WM, Sohal DPS, Taddei TH, Wilson Woods A, Yarchoan M, Rose MG. Gordan JD, et al. J Clin Oncol. 2024 May 20;42(15):1830-1850. doi: 10.1200/JCO.23.02745. Epub 2024 Mar 19. J Clin Oncol. 2024. PMID: 38502889
67 results