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Thrombin-triggered platelet apoptosis.
Leytin V, Allen DJ, Mykhaylov S, Lyubimov E, Freedman J. Leytin V, et al. Among authors: mykhaylov s. J Thromb Haemost. 2006 Dec;4(12):2656-63. doi: 10.1111/j.1538-7836.2006.02200.x. Epub 2006 Sep 8. J Thromb Haemost. 2006. PMID: 16961585 Free article.
The GPIIbIIIa antagonist drugs eptifibatide and tirofiban do not induce activation of apoptosis executioner caspase-3 in resting platelets but inhibit caspase-3 activation in platelets stimulated with thrombin or calcium ionophore A23187.
Leytin V, Mutlu A, Mykhaylov S, Allen DJ, Gyulkhandanyan AV, Freedman J. Leytin V, et al. Among authors: mykhaylov s. Haematologica. 2009 Dec;94(12):1783-4. doi: 10.3324/haematol.2009.012708. Haematologica. 2009. PMID: 19996122 Free PMC article. No abstract available.