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Page 1
Costimulation through the inducible costimulator ligand is essential for both T helper and B cell functions in T cell-dependent B cell responses.
Mak TW, Shahinian A, Yoshinaga SK, Wakeham A, Boucher LM, Pintilie M, Duncan G, Gajewska BU, Gronski M, Eriksson U, Odermatt B, Ho A, Bouchard D, Whorisky JS, Jordana M, Ohashi PS, Pawson T, Bladt F, Tafuri A. Mak TW, et al. Among authors: bladt f. Nat Immunol. 2003 Aug;4(8):765-72. doi: 10.1038/ni947. Epub 2003 Jun 29. Nat Immunol. 2003. PMID: 12833154
ICOS is essential for effective T-helper-cell responses.
Tafuri A, Shahinian A, Bladt F, Yoshinaga SK, Jordana M, Wakeham A, Boucher LM, Bouchard D, Chan VS, Duncan G, Odermatt B, Ho A, Itie A, Horan T, Whoriskey JS, Pawson T, Penninger JM, Ohashi PS, Mak TW. Tafuri A, et al. Among authors: bladt f. Nature. 2001 Jan 4;409(6816):105-9. doi: 10.1038/35051113. Nature. 2001. PMID: 11343123
c-Abl phosphorylates Dok1 to promote filopodia during cell spreading.
Woodring PJ, Meisenhelder J, Johnson SA, Zhou GL, Field J, Shah K, Bladt F, Pawson T, Niki M, Pandolfi PP, Wang JY, Hunter T. Woodring PJ, et al. Among authors: bladt f. J Cell Biol. 2004 May 24;165(4):493-503. doi: 10.1083/jcb.200312171. Epub 2004 May 17. J Cell Biol. 2004. PMID: 15148308 Free PMC article.
Nck adaptors are positive regulators of the size and sensitivity of the T-cell repertoire.
Roy E, Togbe D, Holdorf AD, Trubetskoy D, Nabti S, Küblbeck G, Klevenz A, Kopp-Schneider A, Leithäuser F, Möller P, Bladt F, Hämmerling G, Arnold B, Pawson T, Tafuri A. Roy E, et al. Among authors: bladt f. Proc Natl Acad Sci U S A. 2010 Aug 31;107(35):15529-34. doi: 10.1073/pnas.1009743107. Epub 2010 Aug 13. Proc Natl Acad Sci U S A. 2010. PMID: 20709959 Free PMC article.
Fine tuning of the threshold of T cell selection by the Nck adapters.
Roy E, Togbe D, Holdorf A, Trubetskoy D, Nabti S, Küblbeck G, Schmitt S, Kopp-Schneider A, Leithäuser F, Möller P, Bladt F, Hämmerling GJ, Arnold B, Pawson T, Tafuri A. Roy E, et al. Among authors: bladt f. J Immunol. 2010 Dec 15;185(12):7518-26. doi: 10.4049/jimmunol.1000008. Epub 2010 Nov 15. J Immunol. 2010. PMID: 21078909
35 results