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208 results

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Page 1
Novel bifunctional quinolonyl diketo acid derivatives as HIV-1 integrase inhibitors: design, synthesis, biological activities, and mechanism of action.
Di Santo R, Costi R, Roux A, Artico M, Lavecchia A, Marinelli L, Novellino E, Palmisano L, Andreotti M, Amici R, Galluzzo CM, Nencioni L, Palamara AT, Pommier Y, Marchand C. Di Santo R, et al. Among authors: lavecchia a. J Med Chem. 2006 Mar 23;49(6):1939-45. doi: 10.1021/jm0511583. J Med Chem. 2006. PMID: 16539381 Free PMC article.
Synthesis, molecular modeling, and opioid receptor affinity of 9, 10-diazatricyclo[4.2.1.1(2,5)]decanes and 2,7-diazatricyclo[4.4.0. 0(3,8)]decanes structurally related to 3,8-diazabicyclo[3.2. 1]octanes.
Vianello P, Albinati A, Pinna GA, Lavecchia A, Marinelli L, Borea PA, Gessi S, Fadda P, Tronci S, Cignarella G. Vianello P, et al. Among authors: lavecchia a. J Med Chem. 2000 Jun 1;43(11):2115-23. doi: 10.1021/jm991140q. J Med Chem. 2000. PMID: 10841790
Novel N-(arylalkyl)indol-3-ylglyoxylylamides targeted as ligands of the benzodiazepine receptor: synthesis, biological evaluation, and molecular modeling analysis of the structure-activity relationships.
Primofiore G, Settimo FD, Taliani S, Marini AM, Novellino E, Greco G, Lavecchia A, Besnard F, Trincavelli L, Costa B, Martini C. Primofiore G, et al. Among authors: lavecchia a. J Med Chem. 2001 Jul 5;44(14):2286-97. doi: 10.1021/jm010827j. J Med Chem. 2001. PMID: 11428922
Structure-based design, synthesis, and biological evaluation of conformationally restricted novel 2-alkylthio-6-[1-(2,6-difluorophenyl)alkyl]-3,4-dihydro-5-alkylpyrimidin-4(3H)-ones as non-nucleoside inhibitors of HIV-1 reverse transcriptase.
Mai A, Sbardella G, Artico M, Ragno R, Massa S, Novellino E, Greco G, Lavecchia A, Musiu C, La Colla M, Murgioni C, La Colla P, Loddo R. Mai A, et al. Among authors: lavecchia a. J Med Chem. 2001 Aug 2;44(16):2544-54. doi: 10.1021/jm010853h. J Med Chem. 2001. PMID: 11472208
Design, synthesis and biological evaluation of novel N-alkyl- and N-acyl-(7-substituted-2-phenylimidazo[1,2-a][1,3,5]triazin-4-yl)amines (ITAs) as novel A(1) adenosine receptor antagonists.
Novellino E, Abignente E, Cosimelli B, Greco G, Iadanza M, Laneri S, Lavecchia A, Rimoli MG, Settimo FD, Primofiore G, Tuscano D, Trincavelli L, Martini C. Novellino E, et al. Among authors: lavecchia a. J Med Chem. 2002 Nov 7;45(23):5030-6. doi: 10.1021/jm020911e. J Med Chem. 2002. PMID: 12408713
208 results