Francia G - Search Results

1

Highly efficacious nontoxic preclinical treatment for advanced metastatic breast cancer using combination oral UFT-cyclophosphamide metronomic chemotherapy.

Munoz R, Man S, Shaked Y, Lee CR, Wong J, Francia G, Kerbel RS. Munoz R, et al. Among authors: francia g. Cancer Res. 2006 Apr 1;66(7):3386-91. doi: 10.1158/0008-5472.CAN-05-4411. Cancer Res. 2006. PMID: 16585158

2

Antitumor effects in mice of low-dose (metronomic) cyclophosphamide administered continuously through the drinking water.

Man S, Bocci G, Francia G, Green SK, Jothy S, Hanahan D, Bohlen P, Hicklin DJ, Bergers G, Kerbel RS. Man S, et al. Among authors: francia g. Cancer Res. 2002 May 15;62(10):2731-5. Cancer Res. 2002. PMID: 12019144

3

Thrombospondin 1, a mediator of the antiangiogenic effects of low-dose metronomic chemotherapy.

Bocci G, Francia G, Man S, Lawler J, Kerbel RS. Bocci G, et al. Among authors: francia g. Proc Natl Acad Sci U S A. 2003 Oct 28;100(22):12917-22. doi: 10.1073/pnas.2135406100. Epub 2003 Oct 15. Proc Natl Acad Sci U S A. 2003. PMID: 14561896 Free PMC article.

4

A comparative analysis of low-dose metronomic cyclophosphamide reveals absent or low-grade toxicity on tissues highly sensitive to the toxic effects of maximum tolerated dose regimens.

Emmenegger U, Man S, Shaked Y, Francia G, Wong JW, Hicklin DJ, Kerbel RS. Emmenegger U, et al. Among authors: francia g. Cancer Res. 2004 Jun 1;64(11):3994-4000. doi: 10.1158/0008-5472.CAN-04-0580. Cancer Res. 2004. PMID: 15173013

5

Increased plasma vascular endothelial growth factor (VEGF) as a surrogate marker for optimal therapeutic dosing of VEGF receptor-2 monoclonal antibodies.

Bocci G, Man S, Green SK, Francia G, Ebos JM, du Manoir JM, Weinerman A, Emmenegger U, Ma L, Thorpe P, Davidoff A, Huber J, Hicklin DJ, Kerbel RS. Bocci G, et al. Among authors: francia g. Cancer Res. 2004 Sep 15;64(18):6616-25. doi: 10.1158/0008-5472.CAN-04-0401. Cancer Res. 2004. PMID: 15374976

6

In vitro procoagulant activity induced in endothelial cells by chemotherapy and antiangiogenic drug combinations: modulation by lower-dose chemotherapy.

Ma L, Francia G, Viloria-Petit A, Hicklin DJ, du Manoir J, Rak J, Kerbel RS. Ma L, et al. Among authors: francia g. Cancer Res. 2005 Jun 15;65(12):5365-73. doi: 10.1158/0008-5472.CAN-04-3156. Cancer Res. 2005. PMID: 15958585

7

Low-dose metronomic combined with intermittent bolus-dose cyclophosphamide is an effective long-term chemotherapy treatment strategy.

Shaked Y, Emmenegger U, Francia G, Chen L, Lee CR, Man S, Paraghamian A, Ben-David Y, Kerbel RS. Shaked Y, et al. Among authors: francia g. Cancer Res. 2005 Aug 15;65(16):7045-51. doi: 10.1158/0008-5472.CAN-05-0765. Cancer Res. 2005. PMID: 16103050

8

Down-regulation of DNA mismatch repair proteins in human and murine tumor spheroids: implications for multicellular resistance to alkylating agents.

Francia G, Green SK, Bocci G, Man S, Emmenegger U, Ebos JM, Weinerman A, Shaked Y, Kerbel RS. Francia G, et al. Mol Cancer Ther. 2005 Oct;4(10):1484-94. doi: 10.1158/1535-7163.MCT-04-0214. Mol Cancer Ther. 2005. PMID: 16227397

9

Low-dose metronomic daily cyclophosphamide and weekly tirapazamine: a well-tolerated combination regimen with enhanced efficacy that exploits tumor hypoxia.

Emmenegger U, Morton GC, Francia G, Shaked Y, Franco M, Weinerman A, Man S, Kerbel RS. Emmenegger U, et al. Among authors: francia g. Cancer Res. 2006 Feb 1;66(3):1664-74. doi: 10.1158/0008-5472.CAN-05-2598. Cancer Res. 2006. PMID: 16452226

10

Strategies for delaying or treating in vivo acquired resistance to trastuzumab in human breast cancer xenografts.

du Manoir JM, Francia G, Man S, Mossoba M, Medin JA, Viloria-Petit A, Hicklin DJ, Emmenegger U, Kerbel RS. du Manoir JM, et al. Among authors: francia g. Clin Cancer Res. 2006 Feb 1;12(3 Pt 1):904-16. doi: 10.1158/1078-0432.CCR-05-1109. Clin Cancer Res. 2006. PMID: 16467105

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