Speck NA - Search Results

1

The tetramer structure of the Nervy homology two domain, NHR2, is critical for AML1/ETO's activity.

Liu Y, Cheney MD, Gaudet JJ, Chruszcz M, Lukasik SM, Sugiyama D, Lary J, Cole J, Dauter Z, Minor W, Speck NA, Bushweller JH. Liu Y, et al. Among authors: speck na. Cancer Cell. 2006 Apr;9(4):249-60. doi: 10.1016/j.ccr.2006.03.012. Cancer Cell. 2006. PMID: 16616331 Free article.

2

Structural basis for recognition of SMRT/N-CoR by the MYND domain and its contribution to AML1/ETO's activity.

Liu Y, Chen W, Gaudet J, Cheney MD, Roudaia L, Cierpicki T, Klet RC, Hartman K, Laue TM, Speck NA, Bushweller JH. Liu Y, et al. Among authors: speck na. Cancer Cell. 2007 Jun;11(6):483-97. doi: 10.1016/j.ccr.2007.04.010. Cancer Cell. 2007. PMID: 17560331 Free PMC article.

3

Structure of the AML1-ETO eTAFH domain-HEB peptide complex and its contribution to AML1-ETO activity.

Park S, Chen W, Cierpicki T, Tonelli M, Cai X, Speck NA, Bushweller JH. Park S, et al. Among authors: speck na. Blood. 2009 Apr 9;113(15):3558-67. doi: 10.1182/blood-2008-06-161307. Epub 2009 Feb 9. Blood. 2009. PMID: 19204326 Free PMC article.

4

Structure of the AML1-ETO NHR3-PKA(RIIα) complex and its contribution to AML1-ETO activity.

Corpora T, Roudaia L, Oo ZM, Chen W, Manuylova E, Cai X, Chen MJ, Cierpicki T, Speck NA, Bushweller JH. Corpora T, et al. Among authors: speck na. J Mol Biol. 2010 Sep 24;402(3):560-77. doi: 10.1016/j.jmb.2010.08.007. Epub 2010 Aug 11. J Mol Biol. 2010. PMID: 20708017 Free PMC article.

5

CBFbeta allosterically regulates the Runx1 Runt domain via a dynamic conformational equilibrium.

Yan J, Liu Y, Lukasik SM, Speck NA, Bushweller JH. Yan J, et al. Among authors: speck na. Nat Struct Mol Biol. 2004 Sep;11(9):901-6. doi: 10.1038/nsmb819. Epub 2004 Aug 22. Nat Struct Mol Biol. 2004. PMID: 15322525

6

CBFbeta is critical for AML1-ETO and TEL-AML1 activity.

Roudaia L, Cheney MD, Manuylova E, Chen W, Morrow M, Park S, Lee CT, Kaur P, Williams O, Bushweller JH, Speck NA. Roudaia L, et al. Among authors: speck na. Blood. 2009 Mar 26;113(13):3070-9. doi: 10.1182/blood-2008-03-147207. Epub 2009 Jan 29. Blood. 2009. PMID: 19179469 Free PMC article.

7

The role of CBFbeta in AML1-ETO's activity.

Park S, Speck NA, Bushweller JH. Park S, et al. Among authors: speck na. Blood. 2009 Sep 24;114(13):2849-50. doi: 10.1182/blood-2009-07-231233. Blood. 2009. PMID: 19779050 Free article. No abstract available.

8

Genetic manipulation of AML1-ETO-induced expansion of hematopoietic precursors in a Drosophila model.

Sinenko SA, Hung T, Moroz T, Tran QM, Sidhu S, Cheney MD, Speck NA, Banerjee U. Sinenko SA, et al. Among authors: speck na. Blood. 2010 Nov 25;116(22):4612-20. doi: 10.1182/blood-2010-03-276998. Epub 2010 Aug 5. Blood. 2010. PMID: 20688956 Free PMC article.

9

Altered affinity of CBF beta-SMMHC for Runx1 explains its role in leukemogenesis.

Lukasik SM, Zhang L, Corpora T, Tomanicek S, Li Y, Kundu M, Hartman K, Liu PP, Laue TM, Biltonen RL, Speck NA, Bushweller JH. Lukasik SM, et al. Among authors: speck na. Nat Struct Biol. 2002 Sep;9(9):674-9. doi: 10.1038/nsb831. Nat Struct Biol. 2002. PMID: 12172539

10

Complete heteronuclear NMR resonance assignments and secondary structure of core binding factor beta (1-141).

Huang X, Speck NA, Bushweller JH. Huang X, et al. Among authors: speck na. J Biomol NMR. 1998 Oct;12(3):459-60. doi: 10.1023/a:1008306026814. J Biomol NMR. 1998. PMID: 9835054 No abstract available.

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