Sehested M - Search Results

1

Quantitative proteomic analysis of post-translational modifications of human histones.

Beck HC, Nielsen EC, Matthiesen R, Jensen LH, Sehested M, Finn P, Grauslund M, Hansen AM, Jensen ON. Beck HC, et al. Among authors: sehested m. Mol Cell Proteomics. 2006 Jul;5(7):1314-25. doi: 10.1074/mcp.M600007-MCP200. Epub 2006 Apr 20. Mol Cell Proteomics. 2006. PMID: 16627869 Free article.

2

Proteomic profiling of human colon cancer cells treated with the histone deacetylase inhibitor belinostat.

Beck HC, Petersen J, Nielsen SJ, Morsczeck C, Jensen PB, Sehested M, Grauslund M. Beck HC, et al. Among authors: sehested m. Electrophoresis. 2010 Aug;31(16):2714-21. doi: 10.1002/elps.201000033. Electrophoresis. 2010. PMID: 20717991

3

A three-dimensional quantitative structure-activity relationship study of the inhibition of the ATPase activity and the strand passing catalytic activity of topoisomerase IIalpha by substituted purine analogs.

Jensen LH, Liang H, Shoemaker R, Grauslund M, Sehested M, Hasinoff BB. Jensen LH, et al. Among authors: sehested m. Mol Pharmacol. 2006 Nov;70(5):1503-13. doi: 10.1124/mol.106.026856. Epub 2006 Jul 31. Mol Pharmacol. 2006. PMID: 16880287

4

Differential effects of class I isoform histone deacetylase depletion and enzymatic inhibition by belinostat or valproic acid in HeLa cells.

Dejligbjerg M, Grauslund M, Litman T, Collins L, Qian X, Jeffers M, Lichenstein H, Jensen PB, Sehested M. Dejligbjerg M, et al. Among authors: sehested m. Mol Cancer. 2008 Sep 12;7:70. doi: 10.1186/1476-4598-7-70. Mol Cancer. 2008. PMID: 18789133 Free PMC article.

5

Characterisation of cytotoxicity and DNA damage induced by the topoisomerase II-directed bisdioxopiperazine anti-cancer agent ICRF-187 (dexrazoxane) in yeast and mammalian cells.

Jensen LH, Dejligbjerg M, Hansen LT, Grauslund M, Jensen PB, Sehested M. Jensen LH, et al. Among authors: sehested m. BMC Pharmacol. 2004 Dec 2;4:31. doi: 10.1186/1471-2210-4-31. BMC Pharmacol. 2004. PMID: 15575955 Free PMC article.

6

Separation of bisdioxopiperazine- and vanadate resistance in topoisomerase II.

Sorensen TK, Grauslund M, Jensen PB, Sehested M, Jensen LH. Sorensen TK, et al. Among authors: sehested m. Biochem Biophys Res Commun. 2005 Sep 2;334(3):853-60. doi: 10.1016/j.bbrc.2005.06.177. Biochem Biophys Res Commun. 2005. PMID: 16053917

7

Substituted purine analogues define a novel structural class of catalytic topoisomerase II inhibitors.

Jensen LH, Thougaard AV, Grauslund M, Søkilde B, Carstensen EV, Dvinge HK, Scudiero DA, Jensen PB, Shoemaker RH, Sehested M. Jensen LH, et al. Among authors: sehested m. Cancer Res. 2005 Aug 15;65(16):7470-7. doi: 10.1158/0008-5472.CAN-05-0707. Cancer Res. 2005. PMID: 16103101

8

Identification of predictive biomarkers for the histone deacetylase inhibitor belinostat in a panel of human cancer cell lines.

Dejligbjerg M, Grauslund M, Christensen IJ, Tjørnelund J, Buhl Jensen P, Sehested M. Dejligbjerg M, et al. Among authors: sehested m. Cancer Biomark. 2008;4(2):101-9. doi: 10.3233/cbm-2008-4206. Cancer Biomark. 2008. PMID: 18503161

9

Human small cell lung cancer NYH cells resistant to the bisdioxopiperazine ICRF-187 exhibit a functional dominant Tyr165Ser mutation in the Walker A ATP binding site of topoisomerase II alpha.

Wessel I, Jensen LH, Renodon-Corniere A, Sorensen TK, Nitiss JL, Jensen PB, Sehested M. Wessel I, et al. Among authors: sehested m. FEBS Lett. 2002 Jun 5;520(1-3):161-6. doi: 10.1016/s0014-5793(02)02805-3. FEBS Lett. 2002. PMID: 12044890 Free article.

10

Analysis of bisdioxopiperazine dexrazoxane binding to human DNA topoisomerase II alpha: decreased binding as a mechanism of drug resistance.

Renodon-Cornière A, Jensen LH, Nitiss JL, Jensen PB, Sehested M. Renodon-Cornière A, et al. Among authors: sehested m. Biochemistry. 2003 Aug 19;42(32):9749-54. doi: 10.1021/bi034557d. Biochemistry. 2003. PMID: 12911317

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