Narayanan A - Search Results

1

Conformational changes in protein loops and helices induced by post-translational phosphorylation.

Groban ES, Narayanan A, Jacobson MP. Groban ES, et al. Among authors: narayanan a. PLoS Comput Biol. 2006 Apr;2(4):e32. doi: 10.1371/journal.pcbi.0020032. Epub 2006 Apr 21. PLoS Comput Biol. 2006. PMID: 16628247 Free PMC article.

2

Computational studies of protein regulation by post-translational phosphorylation.

Narayanan A, Jacobson MP. Narayanan A, et al. Curr Opin Struct Biol. 2009 Apr;19(2):156-63. doi: 10.1016/j.sbi.2009.02.007. Epub 2009 Apr 1. Curr Opin Struct Biol. 2009. PMID: 19339172 Review.

3

Phosphorylation of the Arp2 subunit relieves auto-inhibitory interactions for Arp2/3 complex activation.

Narayanan A, LeClaire LL 3rd, Barber DL, Jacobson MP. Narayanan A, et al. PLoS Comput Biol. 2011 Nov;7(11):e1002226. doi: 10.1371/journal.pcbi.1002226. Epub 2011 Nov 10. PLoS Comput Biol. 2011. PMID: 22125478 Free PMC article.

4

Energy-based analysis and prediction of the orientation between light- and heavy-chain antibody variable domains.

Narayanan A, Sellers BD, Jacobson MP. Narayanan A, et al. J Mol Biol. 2009 May 22;388(5):941-53. doi: 10.1016/j.jmb.2009.03.043. Epub 2009 Mar 24. J Mol Biol. 2009. PMID: 19324053

5

Rational targeting of active-site tyrosine residues using sulfonyl fluoride probes.

Hett EC, Xu H, Geoghegan KF, Gopalsamy A, Kyne RE Jr, Menard CA, Narayanan A, Parikh MD, Liu S, Roberts L, Robinson RP, Tones MA, Jones LH. Hett EC, et al. Among authors: narayanan a. ACS Chem Biol. 2015 Apr 17;10(4):1094-8. doi: 10.1021/cb5009475. Epub 2015 Jan 29. ACS Chem Biol. 2015. PMID: 25571984

6

Understanding and applying tyrosine biochemical diversity.

Jones LH, Narayanan A, Hett EC. Jones LH, et al. Among authors: narayanan a. Mol Biosyst. 2014 May;10(5):952-69. doi: 10.1039/c4mb00018h. Mol Biosyst. 2014. PMID: 24623162 Review.

7

A library approach to rapidly discover photoaffinity probes of the mRNA decapping scavenger enzyme DcpS.

Xu H, Hett EC, Gopalsamy A, Parikh MD, Geoghegan KF, Kyne RE Jr, Menard CA, Narayanan A, Robinson RP, Johnson DS, Tones MA, Jones LH. Xu H, et al. Among authors: narayanan a. Mol Biosyst. 2015 Oct;11(10):2709-12. doi: 10.1039/c5mb00288e. Mol Biosyst. 2015. PMID: 25959423

8

Design of Potent mRNA Decapping Scavenger Enzyme (DcpS) Inhibitors with Improved Physicochemical Properties To Investigate the Mechanism of Therapeutic Benefit in Spinal Muscular Atrophy (SMA).

Gopalsamy A, Narayanan A, Liu S, Parikh MD, Kyne RE Jr, Fadeyi O, Tones MA, Cherry JJ, Nabhan JF, LaRosa G, Petersen DN, Menard C, Foley TL, Noell S, Ren Y, Loria PM, Maglich-Goodwin J, Rong H, Jones LH. Gopalsamy A, et al. Among authors: narayanan a. J Med Chem. 2017 Apr 13;60(7):3094-3108. doi: 10.1021/acs.jmedchem.7b00124. Epub 2017 Mar 16. J Med Chem. 2017. PMID: 28257199

9

Sulfonyl fluorides as privileged warheads in chemical biology.

Narayanan A, Jones LH. Narayanan A, et al. Chem Sci. 2015 May 1;6(5):2650-2659. doi: 10.1039/c5sc00408j. Epub 2015 Mar 16. Chem Sci. 2015. PMID: 28706662 Free PMC article.

10

Quantitative measurement of intracellular HDAC1/2 drug occupancy using a trans-cyclooctene largazole thiol probe.

Xu H, Roberts LR, Chou S, Pierce B, Narayanan A, Jones LH. Xu H, et al. Among authors: narayanan a. Medchemcomm. 2017 Jan 9;8(4):767-770. doi: 10.1039/c6md00633g. eCollection 2017 Apr 1. Medchemcomm. 2017. PMID: 30108795 Free PMC article.

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