Zhang J - Search Results

1

New potential antimalarial agents: therapeutic-index evaluation of pyrroloquinazolinediamine and its prodrugs in a rat model of severe malaria.

Xie LH, Li Q, Lin AJ, Smith K, Zhang J, Skillman DS. Xie LH, et al. Among authors: zhang j. Antimicrob Agents Chemother. 2006 May;50(5):1649-55. doi: 10.1128/AAC.50.5.1649-1655.2006. Antimicrob Agents Chemother. 2006. PMID: 16641431 Free PMC article.

2

The evaluation of radiolabeled artesunate on tissue distribution in rats and protein binding in humans.

Li Q, Xie LH, Haeberle A, Zhang J, Weina P. Li Q, et al. Among authors: zhang j. Am J Trop Med Hyg. 2006 Nov;75(5):817-26. Am J Trop Med Hyg. 2006. PMID: 17123971

3

Development and validation of flow cytometric measurement for parasitemia in cultures of P. falciparum vitally stained with YOYO-1.

Li Q, Gerena L, Xie L, Zhang J, Kyle D, Milhous W. Li Q, et al. Among authors: zhang j. Cytometry A. 2007 May;71(5):297-307. doi: 10.1002/cyto.a.20380. Cytometry A. 2007. PMID: 17279569 Free article.

4

Pharmacokinetics, safety, and hydrolysis of oral pyrroloquinazolinediamines administered in single and multiple doses in rats.

Li Q, Kozar MP, Shearer TW, Xie LH, Lin AJ, Smith KS, Si Y, Anova L, Zhang J, Milhous WK, Skillman DR. Li Q, et al. Among authors: zhang j. Antimicrob Agents Chemother. 2007 Aug;51(8):2898-904. doi: 10.1128/AAC.00932-06. Epub 2007 Jun 11. Antimicrob Agents Chemother. 2007. PMID: 17562804 Free PMC article.

5

Pharmacokinetic and pharmacodynamic evaluation of intramuscular artesunate in healthy beagle dogs.

Bennett K, Si Y, Steinbach T, Zhang J, Li Q. Bennett K, et al. Among authors: zhang j. Am J Trop Med Hyg. 2008 Jul;79(1):36-41. Am J Trop Med Hyg. 2008. PMID: 18606761

6

The distribution pattern of intravenous [(14)C] artesunate in rat tissues by quantitative whole-body autoradiography and tissue dissection techniques.

Li Q, Xie L, Zhang J, Weina PJ. Li Q, et al. Among authors: zhang j. J Pharm Biomed Anal. 2008 Nov 4;48(3):876-84. doi: 10.1016/j.jpba.2008.07.015. Epub 2008 Jul 30. J Pharm Biomed Anal. 2008. PMID: 18762400

7

Pharmacokinetics, tissue distribution and mass balance of radiolabeled dihydroartemisinin in male rats.

Xie LH, Li Q, Zhang J, Weina PJ. Xie LH, et al. Among authors: zhang j. Malar J. 2009 May 26;8:112. doi: 10.1186/1475-2875-8-112. Malar J. 2009. PMID: 19470172 Free PMC article.

8

Severe embryolethality of artesunate related to pharmacokinetics following intravenous and intramuscular doses in pregnant rats.

Li Q, Si Y, Xie L, Zhang J, Weina P. Li Q, et al. Among authors: zhang j. Birth Defects Res B Dev Reprod Toxicol. 2009 Oct;86(5):385-93. doi: 10.1002/bdrb.20207. Birth Defects Res B Dev Reprod Toxicol. 2009. PMID: 19851989

9

In vitro biotransformation, in vivo efficacy and pharmacokinetics of antimalarial chalcones.

Gutteridge CE, Thota DS, Curtis SM, Kozar MP, Li Q, Xie L, Zhang J, Melendez V, Asher CO, Luong TT, Gerena L, Nichols DA, Montip G. Gutteridge CE, et al. Among authors: zhang j. Pharmacology. 2011;87(1-2):96-104. doi: 10.1159/000322532. Epub 2011 Feb 1. Pharmacology. 2011. PMID: 21282967

10

Formulation and particle size reduction improve bioavailability of poorly water-soluble compounds with antimalarial activity.

Wang H, Li Q, Reyes S, Zhang J, Xie L, Melendez V, Hickman M, Kozar MP. Wang H, et al. Among authors: zhang j. Malar Res Treat. 2013;2013:769234. doi: 10.1155/2013/769234. Epub 2013 May 12. Malar Res Treat. 2013. PMID: 23766925 Free PMC article.

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