Penaranda C - Search Results

1

Diarylureas are small-molecule inhibitors of insulin-like growth factor I receptor signaling and breast cancer cell growth.

Gable KL, Maddux BA, Penaranda C, Zavodovskaya M, Campbell MJ, Lobo M, Robinson L, Schow S, Kerner JA, Goldfine ID, Youngren JF. Gable KL, et al. Among authors: penaranda c. Mol Cancer Ther. 2006 Apr;5(4):1079-86. doi: 10.1158/1535-7163.MCT-05-0397. Mol Cancer Ther. 2006. PMID: 16648580

2

Nordihydroguaiaretic acid (NDGA) inhibits the IGF-1 and c-erbB2/HER2/neu receptors and suppresses growth in breast cancer cells.

Youngren JF, Gable K, Penaranda C, Maddux BA, Zavodovskaya M, Lobo M, Campbell M, Kerner J, Goldfine ID. Youngren JF, et al. Among authors: penaranda c. Breast Cancer Res Treat. 2005 Nov;94(1):37-46. doi: 10.1007/s10549-005-6939-z. Breast Cancer Res Treat. 2005. PMID: 16142439

3

Parallel synthesis of diarylureas and their evaluation as inhibitors of insulin-like growth factor receptor.

Anderson MO, Yu H, Penaranda C, Maddux BA, Goldfine ID, Youngren JF, Guy RK. Anderson MO, et al. Among authors: penaranda c. J Comb Chem. 2006 Sep-Oct;8(5):784-90. doi: 10.1021/cc050136z. J Comb Chem. 2006. PMID: 16961415

4

Inhibition of IGF-1R and lipoxygenase by nordihydroguaiaretic acid (NDGA) analogs.

Blecha JE, Anderson MO, Chow JM, Guevarra CC, Pender C, Penaranda C, Zavodovskaya M, Youngren JF, Berkman CE. Blecha JE, et al. Among authors: penaranda c. Bioorg Med Chem Lett. 2007 Jul 15;17(14):4026-9. doi: 10.1016/j.bmcl.2007.04.092. Epub 2007 Apr 29. Bioorg Med Chem Lett. 2007. PMID: 17502145 Free PMC article.

5

Anti-CD3 therapy promotes tolerance by selectively depleting pathogenic cells while preserving regulatory T cells.

Penaranda C, Tang Q, Bluestone JA. Penaranda C, et al. J Immunol. 2011 Aug 15;187(4):2015-22. doi: 10.4049/jimmunol.1100713. Epub 2011 Jul 8. J Immunol. 2011. PMID: 21742976 Free PMC article.

6

IL-7 receptor blockade reverses autoimmune diabetes by promoting inhibition of effector/memory T cells.

Penaranda C, Kuswanto W, Hofmann J, Kenefeck R, Narendran P, Walker LS, Bluestone JA, Abbas AK, Dooms H. Penaranda C, et al. Proc Natl Acad Sci U S A. 2012 Jul 31;109(31):12668-73. doi: 10.1073/pnas.1203692109. Epub 2012 Jun 25. Proc Natl Acad Sci U S A. 2012. PMID: 22733744 Free PMC article.

7

Aberrant innate immune activation following tissue injury impairs pancreatic regeneration.

Folias AE, Penaranda C, Su AL, Bluestone JA, Hebrok M. Folias AE, et al. Among authors: penaranda c. PLoS One. 2014 Jul 10;9(7):e102125. doi: 10.1371/journal.pone.0102125. eCollection 2014. PLoS One. 2014. PMID: 25010227 Free PMC article.

8

Prevention of diabetes by FTY720-mediated stabilization of peri-islet tertiary lymphoid organs.

Penaranda C, Tang Q, Ruddle NH, Bluestone JA. Penaranda C, et al. Diabetes. 2010 Jun;59(6):1461-8. doi: 10.2337/db09-1129. Epub 2010 Mar 18. Diabetes. 2010. PMID: 20299465 Free PMC article.

9

Instability of the transcription factor Foxp3 leads to the generation of pathogenic memory T cells in vivo.

Zhou X, Bailey-Bucktrout SL, Jeker LT, Penaranda C, Martínez-Llordella M, Ashby M, Nakayama M, Rosenthal W, Bluestone JA. Zhou X, et al. Among authors: penaranda c. Nat Immunol. 2009 Sep;10(9):1000-7. doi: 10.1038/ni.1774. Epub 2009 Jul 26. Nat Immunol. 2009. PMID: 19633673 Free PMC article.

10

Central role of defective interleukin-2 production in the triggering of islet autoimmune destruction.

Tang Q, Adams JY, Penaranda C, Melli K, Piaggio E, Sgouroudis E, Piccirillo CA, Salomon BL, Bluestone JA. Tang Q, et al. Among authors: penaranda c. Immunity. 2008 May;28(5):687-97. doi: 10.1016/j.immuni.2008.03.016. Epub 2008 May 8. Immunity. 2008. PMID: 18468463 Free PMC article.

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