Kim KT - Search Results

1

IMC-EB10, an anti-FLT3 monoclonal antibody, prolongs survival and reduces nonobese diabetic/severe combined immunodeficient engraftment of some acute lymphoblastic leukemia cell lines and primary leukemic samples.

Piloto O, Nguyen B, Huso D, Kim KT, Li Y, Witte L, Hicklin DJ, Brown P, Small D. Piloto O, et al. Among authors: kim kt. Cancer Res. 2006 May 1;66(9):4843-51. doi: 10.1158/0008-5472.CAN-06-0018. Cancer Res. 2006. PMID: 16651440

2

Prolonged exposure to FLT3 inhibitors leads to resistance via activation of parallel signaling pathways.

Piloto O, Wright M, Brown P, Kim KT, Levis M, Small D. Piloto O, et al. Among authors: kim kt. Blood. 2007 Feb 15;109(4):1643-52. doi: 10.1182/blood-2006-05-023804. Epub 2006 Oct 17. Blood. 2007. PMID: 17047150 Free PMC article.

3

Pim-1 is up-regulated by constitutively activated FLT3 and plays a role in FLT3-mediated cell survival.

Kim KT, Baird K, Ahn JY, Meltzer P, Lilly M, Levis M, Small D. Kim KT, et al. Blood. 2005 Feb 15;105(4):1759-67. doi: 10.1182/blood-2004-05-2006. Epub 2004 Oct 21. Blood. 2005. PMID: 15498859 Free article.

4

FLT3/ITD mutation signaling includes suppression of SHP-1.

Chen P, Levis M, Brown P, Kim KT, Allebach J, Small D. Chen P, et al. Among authors: kim kt. J Biol Chem. 2005 Feb 18;280(7):5361-9. doi: 10.1074/jbc.M411974200. Epub 2004 Dec 1. J Biol Chem. 2005. PMID: 15574429 Free article.

5

Internal tandem duplications of the FLT3 gene are present in leukemia stem cells.

Levis M, Murphy KM, Pham R, Kim KT, Stine A, Li L, McNiece I, Smith BD, Small D. Levis M, et al. Among authors: kim kt. Blood. 2005 Jul 15;106(2):673-80. doi: 10.1182/blood-2004-05-1902. Epub 2005 Mar 29. Blood. 2005. PMID: 15797998 Free PMC article.

6

Constitutively activated FLT3 phosphorylates BAD partially through pim-1.

Kim KT, Levis M, Small D. Kim KT, et al. Br J Haematol. 2006 Sep;134(5):500-9. doi: 10.1111/j.1365-2141.2006.06225.x. Br J Haematol. 2006. PMID: 16869825 Free article.

7

FLT3/ITD expression increases expansion, survival and entry into cell cycle of human haematopoietic stem/progenitor cells.

Li L, Piloto O, Kim KT, Ye Z, Nguyen HB, Yu X, Levis M, Cheng L, Small D. Li L, et al. Among authors: kim kt. Br J Haematol. 2007 Apr;137(1):64-75. doi: 10.1111/j.1365-2141.2007.06525.x. Br J Haematol. 2007. PMID: 17359372 Free article.

8

Constitutive Fms-like tyrosine kinase 3 activation results in specific changes in gene expression in myeloid leukaemic cells.

Kim KT, Baird K, Davis S, Piloto O, Levis M, Li L, Chen P, Meltzer P, Small D. Kim KT, et al. Br J Haematol. 2007 Sep;138(5):603-15. doi: 10.1111/j.1365-2141.2007.06696.x. Br J Haematol. 2007. PMID: 17686054 Free article.

9

Internal tandem duplication of FLT3 (FLT3/ITD) induces increased ROS production, DNA damage, and misrepair: implications for poor prognosis in AML.

Sallmyr A, Fan J, Datta K, Kim KT, Grosu D, Shapiro P, Small D, Rassool F. Sallmyr A, et al. Among authors: kim kt. Blood. 2008 Mar 15;111(6):3173-82. doi: 10.1182/blood-2007-05-092510. Epub 2008 Jan 11. Blood. 2008. PMID: 18192505 Free article.

10

MicroRNA-16 is down-regulated in mutated FLT3 expressing murine myeloid FDC-P1 cells and interacts with Pim-1.

Kim KT, Carroll AP, Mashkani B, Cairns MJ, Small D, Scott RJ. Kim KT, et al. PLoS One. 2012;7(9):e44546. doi: 10.1371/journal.pone.0044546. Epub 2012 Sep 6. PLoS One. 2012. PMID: 22970245 Free PMC article.

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