Cua DJ - Search Results

1

IL-23 is essential for T cell-mediated colitis and promotes inflammation via IL-17 and IL-6.

Yen D, Cheung J, Scheerens H, Poulet F, McClanahan T, McKenzie B, Kleinschek MA, Owyang A, Mattson J, Blumenschein W, Murphy E, Sathe M, Cua DJ, Kastelein RA, Rennick D. Yen D, et al. Among authors: cua dj. J Clin Invest. 2006 May;116(5):1310-6. doi: 10.1172/JCI21404. J Clin Invest. 2006. PMID: 16670770 Free PMC article.

2

Interleukin-23 rather than interleukin-12 is the critical cytokine for autoimmune inflammation of the brain.

Cua DJ, Sherlock J, Chen Y, Murphy CA, Joyce B, Seymour B, Lucian L, To W, Kwan S, Churakova T, Zurawski S, Wiekowski M, Lira SA, Gorman D, Kastelein RA, Sedgwick JD. Cua DJ, et al. Nature. 2003 Feb 13;421(6924):744-8. doi: 10.1038/nature01355. Nature. 2003. PMID: 12610626

3

Divergent pro- and antiinflammatory roles for IL-23 and IL-12 in joint autoimmune inflammation.

Murphy CA, Langrish CL, Chen Y, Blumenschein W, McClanahan T, Kastelein RA, Sedgwick JD, Cua DJ. Murphy CA, et al. Among authors: cua dj. J Exp Med. 2003 Dec 15;198(12):1951-7. doi: 10.1084/jem.20030896. Epub 2003 Dec 8. J Exp Med. 2003. PMID: 14662908 Free PMC article.

4

IL-23 provides a limited mechanism of resistance to acute toxoplasmosis in the absence of IL-12.

Lieberman LA, Cardillo F, Owyang AM, Rennick DM, Cua DJ, Kastelein RA, Hunter CA. Lieberman LA, et al. Among authors: cua dj. J Immunol. 2004 Aug 1;173(3):1887-93. doi: 10.4049/jimmunol.173.3.1887. J Immunol. 2004. PMID: 15265921

5

IL-12 and IL-23: master regulators of innate and adaptive immunity.

Langrish CL, McKenzie BS, Wilson NJ, de Waal Malefyt R, Kastelein RA, Cua DJ. Langrish CL, et al. Among authors: cua dj. Immunol Rev. 2004 Dec;202:96-105. doi: 10.1111/j.0105-2896.2004.00214.x. Immunol Rev. 2004. PMID: 15546388 Review.

6

IL-23 drives a pathogenic T cell population that induces autoimmune inflammation.

Langrish CL, Chen Y, Blumenschein WM, Mattson J, Basham B, Sedgwick JD, McClanahan T, Kastelein RA, Cua DJ. Langrish CL, et al. Among authors: cua dj. J Exp Med. 2005 Jan 17;201(2):233-40. doi: 10.1084/jem.20041257. J Exp Med. 2005. PMID: 15657292 Free PMC article.

7

Understanding the IL-23-IL-17 immune pathway.

McKenzie BS, Kastelein RA, Cua DJ. McKenzie BS, et al. Among authors: cua dj. Trends Immunol. 2006 Jan;27(1):17-23. doi: 10.1016/j.it.2005.10.003. Epub 2005 Nov 14. Trends Immunol. 2006. PMID: 16290228

8

Interleukin 25 regulates type 2 cytokine-dependent immunity and limits chronic inflammation in the gastrointestinal tract.

Owyang AM, Zaph C, Wilson EH, Guild KJ, McClanahan T, Miller HR, Cua DJ, Goldschmidt M, Hunter CA, Kastelein RA, Artis D. Owyang AM, et al. Among authors: cua dj. J Exp Med. 2006 Apr 17;203(4):843-9. doi: 10.1084/jem.20051496. Epub 2006 Apr 10. J Exp Med. 2006. PMID: 16606667 Free PMC article.

9

Rationale and safety of anti-interleukin-23 and anti-interleukin-17A therapy.

Bowman EP, Chackerian AA, Cua DJ. Bowman EP, et al. Among authors: cua dj. Curr Opin Infect Dis. 2006 Jun;19(3):245-52. doi: 10.1097/01.qco.0000224818.42729.67. Curr Opin Infect Dis. 2006. PMID: 16645485 Review.

10

Anti-IL-23 therapy inhibits multiple inflammatory pathways and ameliorates autoimmune encephalomyelitis.

Chen Y, Langrish CL, McKenzie B, Joyce-Shaikh B, Stumhofer JS, McClanahan T, Blumenschein W, Churakovsa T, Low J, Presta L, Hunter CA, Kastelein RA, Cua DJ. Chen Y, et al. Among authors: cua dj. J Clin Invest. 2006 May;116(5):1317-26. doi: 10.1172/JCI25308. J Clin Invest. 2006. PMID: 16670771 Free PMC article.

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