Conformational modification of serpins transforms leukocyte elastase inhibitor into an endonuclease involved in apoptosis.
Padron-Barthe L, Leprêtre C, Martin E, Counis MF, Torriglia A.
Padron-Barthe L, et al. Among authors: torriglia a.
Mol Cell Biol. 2007 Jun;27(11):4028-36. doi: 10.1128/MCB.01959-06. Epub 2007 Apr 2.
Mol Cell Biol. 2007.
PMID: 17403905
Free PMC article.
We have thus shown that this endonuclease derives from the serpin superfamily member LEI by posttranslational modification (A. Torriglia, P. Perani, J. Y. Brossas, E. Chaudun, J. Treton, Y. Courtois, and M. F. ...This represents a novel molecular mechanism fo …
We have thus shown that this endonuclease derives from the serpin superfamily member LEI by posttranslational modification (A. Tor …