O'Shea JJ - Search Results

1

Selective regulatory function of Socs3 in the formation of IL-17-secreting T cells.

Chen Z, Laurence A, Kanno Y, Pacher-Zavisin M, Zhu BM, Tato C, Yoshimura A, Hennighausen L, O'Shea JJ. Chen Z, et al. Proc Natl Acad Sci U S A. 2006 May 23;103(21):8137-42. doi: 10.1073/pnas.0600666103. Epub 2006 May 12. Proc Natl Acad Sci U S A. 2006. PMID: 16698929 Free PMC article.

2

Keegan AD, Johnston JA, Tortolani PJ, McReynolds LJ, Kinzer C, O'Shea JJ, Paul WE. Keegan AD, et al. Proc Natl Acad Sci U S A. 1995 Aug 15;92(17):7681-5. doi: 10.1073/pnas.92.17.7681. Proc Natl Acad Sci U S A. 1995. PMID: 7544000 Free PMC article.

3

Interleukin 12 induces tyrosine phosphorylation and activation of STAT4 in human lymphocytes.

Bacon CM, Petricoin EF 3rd, Ortaldo JR, Rees RC, Larner AC, Johnston JA, O'Shea JJ. Bacon CM, et al. Proc Natl Acad Sci U S A. 1995 Aug 1;92(16):7307-11. doi: 10.1073/pnas.92.16.7307. Proc Natl Acad Sci U S A. 1995. PMID: 7638186 Free PMC article.

4

Activation of STAT4 by IL-12 and IFN-alpha: evidence for the involvement of ligand-induced tyrosine and serine phosphorylation.

Cho SS, Bacon CM, Sudarshan C, Rees RC, Finbloom D, Pine R, O'Shea JJ. Cho SS, et al. J Immunol. 1996 Dec 1;157(11):4781-9. J Immunol. 1996. PMID: 8943379

5

Signaling via IL-2 and IL-4 in JAK3-deficient severe combined immunodeficiency lymphocytes: JAK3-dependent and independent pathways.

Oakes SA, Candotti F, Johnston JA, Chen YQ, Ryan JJ, Taylor N, Liu X, Hennighausen L, Notarangelo LD, Paul WE, Blaese RM, O'Shea JJ. Oakes SA, et al. Immunity. 1996 Dec;5(6):605-15. doi: 10.1016/s1074-7613(00)80274-5. Immunity. 1996. PMID: 8986719 Free article.

6

The amino terminus of JAK3 is necessary and sufficient for binding to the common gamma chain and confers the ability to transmit interleukin 2-mediated signals.

Chen M, Cheng A, Chen YQ, Hymel A, Hanson EP, Kimmel L, Minami Y, Taniguchi T, Changelian PS, O'Shea JJ. Chen M, et al. Proc Natl Acad Sci U S A. 1997 Jun 24;94(13):6910-5. doi: 10.1073/pnas.94.13.6910. Proc Natl Acad Sci U S A. 1997. PMID: 9192665 Free PMC article.

7

Distinct tyrosine phosphorylation sites in JAK3 kinase domain positively and negatively regulate its enzymatic activity.

Zhou YJ, Hanson EP, Chen YQ, Magnuson K, Chen M, Swann PG, Wange RL, Changelian PS, O'Shea JJ. Zhou YJ, et al. Proc Natl Acad Sci U S A. 1997 Dec 9;94(25):13850-5. doi: 10.1073/pnas.94.25.13850. Proc Natl Acad Sci U S A. 1997. PMID: 9391116 Free PMC article.

8

TGF-beta does not inhibit IL-12- and IL-2-induced activation of Janus kinases and STATs.

Sudarshan C, Galon J, Zhou Y, O'Shea JJ. Sudarshan C, et al. J Immunol. 1999 Mar 1;162(5):2974-81. J Immunol. 1999. PMID: 10072548

9

IL-12 induces IFN regulating factor-1 (IRF-1) gene expression in human NK and T cells.

Galon J, Sudarshan C, Ito S, Finbloom D, O'Shea JJ. Galon J, et al. J Immunol. 1999 Jun 15;162(12):7256-62. J Immunol. 1999. PMID: 10358173

10

IFN consensus sequence binding protein potentiates STAT1-dependent activation of IFNgamma-responsive promoters in macrophages.

Contursi C, Wang IM, Gabriele L, Gadina M, O'Shea J, Morse HC 3rd, Ozato K. Contursi C, et al. Proc Natl Acad Sci U S A. 2000 Jan 4;97(1):91-6. doi: 10.1073/pnas.97.1.91. Proc Natl Acad Sci U S A. 2000. PMID: 10618376 Free PMC article.

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