Lu X - Search Results

1

ASPP2 is a haploinsufficient tumor suppressor that cooperates with p53 to suppress tumor growth.

Vives V, Su J, Zhong S, Ratnayaka I, Slee E, Goldin R, Lu X. Vives V, et al. Among authors: lu x. Genes Dev. 2006 May 15;20(10):1262-7. doi: 10.1101/gad.374006. Genes Dev. 2006. PMID: 16702401 Free PMC article.

2

Physical and functional interactions between p53 and cell cycle co-operating transcription factors, E2F1 and DP1.

O'Connor DJ, Lam EW, Griffin S, Zhong S, Leighton LC, Burbidge SA, Lu X. O'Connor DJ, et al. Among authors: lu x. EMBO J. 1995 Dec 15;14(24):6184-92. doi: 10.1002/j.1460-2075.1995.tb00309.x. EMBO J. 1995. PMID: 8557038 Free PMC article.

3

E2F1-induced apoptosis requires DNA binding but not transactivation and is inhibited by the retinoblastoma protein through direct interaction.

Hsieh JK, Fredersdorf S, Kouzarides T, Martin K, Lu X. Hsieh JK, et al. Among authors: lu x. Genes Dev. 1997 Jul 15;11(14):1840-52. doi: 10.1101/gad.11.14.1840. Genes Dev. 1997. PMID: 9242491 Free article.

4

RB regulates the stability and the apoptotic function of p53 via MDM2.

Hsieh JK, Chan FS, O'Connor DJ, Mittnacht S, Zhong S, Lu X. Hsieh JK, et al. Among authors: lu x. Mol Cell. 1999 Feb;3(2):181-93. doi: 10.1016/s1097-2765(00)80309-3. Mol Cell. 1999. PMID: 10078201 Free article.

5

ASPP proteins specifically stimulate the apoptotic function of p53.

Samuels-Lev Y, O'Connor DJ, Bergamaschi D, Trigiante G, Hsieh JK, Zhong S, Campargue I, Naumovski L, Crook T, Lu X. Samuels-Lev Y, et al. Among authors: lu x. Mol Cell. 2001 Oct;8(4):781-94. doi: 10.1016/s1097-2765(01)00367-7. Mol Cell. 2001. PMID: 11684014 Free article.

6

Novel function of the cyclin A binding site of E2F in regulating p53-induced apoptosis in response to DNA damage.

Hsieh JK, Yap D, O'Connor DJ, Fogal V, Fallis L, Chan F, Zhong S, Lu X. Hsieh JK, et al. Among authors: lu x. Mol Cell Biol. 2002 Jan;22(1):78-93. doi: 10.1128/MCB.22.1.78-93.2002. Mol Cell Biol. 2002. PMID: 11739724 Free PMC article.

7

iASPP oncoprotein is a key inhibitor of p53 conserved from worm to human.

Bergamaschi D, Samuels Y, O'Neil NJ, Trigiante G, Crook T, Hsieh JK, O'Connor DJ, Zhong S, Campargue I, Tomlinson ML, Kuwabara PE, Lu X. Bergamaschi D, et al. Among authors: lu x. Nat Genet. 2003 Feb;33(2):162-7. doi: 10.1038/ng1070. Epub 2003 Jan 13. Nat Genet. 2003. PMID: 12524540

8

The ASPP family: deciding between life and death after DNA damage.

Slee EA, Lu X. Slee EA, et al. Among authors: lu x. Toxicol Lett. 2003 Apr 4;139(2-3):81-7. doi: 10.1016/s0378-4274(02)00421-6. Toxicol Lett. 2003. PMID: 12628742 Review.

9

The biological response of MCF7 breast cancer cells to proteosome inhibition or gamma-radiation is unrelated to the level of p53 induction.

Fallis LH, Richards E, O'Connor DJ, Zhong S, Hsieh JK, Packham G, Lu X. Fallis LH, et al. Among authors: lu x. Apoptosis. 1999 Apr;4(2):99-107. doi: 10.1023/a:1009614726059. Apoptosis. 1999. PMID: 14634287

10

ASPP1 and ASPP2: common activators of p53 family members.

Bergamaschi D, Samuels Y, Jin B, Duraisingham S, Crook T, Lu X. Bergamaschi D, et al. Among authors: lu x. Mol Cell Biol. 2004 Feb;24(3):1341-50. doi: 10.1128/MCB.24.3.1341-1350.2004. Mol Cell Biol. 2004. PMID: 14729977 Free PMC article.

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