Aquino M - Search Results

1

Chemistry and biology of chromatin remodeling agents: state of art and future perspectives of HDAC inhibitors.

Rodriquez M, Aquino M, Bruno I, De Martino G, Taddei M, Gomez-Paloma L. Rodriquez M, et al. Among authors: aquino m. Curr Med Chem. 2006;13(10):1119-39. doi: 10.2174/092986706776360905. Curr Med Chem. 2006. PMID: 16719774 Review.

2

Chemistry and biology of anti-inflammatory marine natural products: molecules interfering with cyclooxygenase, NF-kappaB and other unidentified targets.

Terracciano S, Aquino M, Rodriquez M, Monti MC, Casapullo A, Riccio R, Gomez-Paloma L. Terracciano S, et al. Among authors: aquino m. Curr Med Chem. 2006;13(16):1947-69. doi: 10.2174/092986706777585095. Curr Med Chem. 2006. PMID: 16842204 Review.

3

Synthesis and pharmacological evaluation of a selected library of new potential anti-inflammatory agents bearing the gamma-hydroxybutenolide scaffold: a new class of inhibitors of prostanoid production through the selective modulation of microsomal prostaglandin E synthase-1 expression.

Guerrero MD, Aquino M, Bruno I, Terencio MC, Paya M, Riccio R, Gomez-Paloma L. Guerrero MD, et al. Among authors: aquino m. J Med Chem. 2007 May 3;50(9):2176-84. doi: 10.1021/jm0700823. Epub 2007 Apr 4. J Med Chem. 2007. PMID: 17407277

4

Development of a second generation of inhibitors of microsomal prostaglandin E synthase 1 expression bearing the gamma-hydroxybutenolide scaffold.

Aquino M, Guerrero MD, Bruno I, Terencio MC, Paya M, Riccio R. Aquino M, et al. Bioorg Med Chem. 2008 Oct 1;16(19):9056-64. doi: 10.1016/j.bmc.2008.08.001. Epub 2008 Aug 6. Bioorg Med Chem. 2008. PMID: 18790649

5

Regioselective entry to bromo-gamma-hydroxybutenolides: useful building blocks for assemblying natural product-like libraries.

Aquino M, Bruno I, Riccio R, Gomez-Paloma L. Aquino M, et al. Org Lett. 2006 Oct 12;8(21):4831-4. doi: 10.1021/ol0618611. Org Lett. 2006. PMID: 17020314

6

Toward the discovery of new agents able to inhibit the expression of microsomal prostaglandin E synthase-1 enzyme as promising tools in drug development.

De Simone R, Andrés RM, Aquino M, Bruno I, Guerrero MD, Terencio MC, Paya M, Riccio R. De Simone R, et al. Among authors: aquino m. Chem Biol Drug Des. 2010 Jul;76(1):17-24. doi: 10.1111/j.1747-0285.2010.00984.x. Epub 2010 Apr 28. Chem Biol Drug Des. 2010. PMID: 20492447

7

Anti-inflammatory and analgesic activity of a novel inhibitor of microsomal prostaglandin E synthase-1 expression.

Guerrero MD, Aquino M, Bruno I, Riccio R, Terencio MC, Payá M. Guerrero MD, et al. Among authors: aquino m. Eur J Pharmacol. 2009 Oct 12;620(1-3):112-9. doi: 10.1016/j.ejphar.2009.08.007. Epub 2009 Aug 15. Eur J Pharmacol. 2009. PMID: 19686718

8

A new rational hypothesis for the pharmacophore of the active metabolite of leflunomide, a potent immunosuppressive drug.

Bertolini G, Aquino M, Biffi M, d'Atri G, Di Pierro F, Ferrario F, Mascagni P, Somenzi F, Zaliani A, Leoni F. Bertolini G, et al. Among authors: aquino m. J Med Chem. 1997 Jun 20;40(13):2011-6. doi: 10.1021/jm970039n. J Med Chem. 1997. PMID: 9207942

9

Enantioselective synthesis of iridal, the parent molecule of the iridal triterpenoid class.

Corbu A, Aquino M, Pratap TV, Retailleau P, Arseniyadis S. Corbu A, et al. Among authors: aquino m. Org Lett. 2008 May 1;10(9):1787-90. doi: 10.1021/ol8005425. Epub 2008 Apr 9. Org Lett. 2008. PMID: 18396888

10

Competing domino processes: path-discriminating ability of epoxide stereochemistry at the angular position.

Aquino M, Safir I, Elkhayat Z, Gandara Z, Perez M, Retailleau P, Arseniyadis S. Aquino M, et al. Org Lett. 2009 Aug 20;11(16):3610-3. doi: 10.1021/ol9013377. Org Lett. 2009. PMID: 19719199

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