James CH - Search Results

1

Novel candidate genes in unstable areas of human atherosclerotic plaques.

Papaspyridonos M, Smith A, Burnand KG, Taylor P, Padayachee S, Suckling KE, James CH, Greaves DR, Patel L. Papaspyridonos M, et al. Among authors: james ch. Arterioscler Thromb Vasc Biol. 2006 Aug;26(8):1837-44. doi: 10.1161/01.ATV.0000229695.68416.76. Epub 2006 Jun 1. Arterioscler Thromb Vasc Biol. 2006. PMID: 16741146

2

Human tribbles homologue 2 is expressed in unstable regions of carotid plaques and regulates macrophage IL-10 in vitro.

Deng J, James CH, Patel L, Smith A, Burnand KG, Rahmoune H, Lamb JR, Davis B. Deng J, et al. Among authors: james ch. Clin Sci (Lond). 2009 Feb;116(3):241-8. doi: 10.1042/CS20080058. Clin Sci (Lond). 2009. PMID: 18643775

3

Identification of a Human Whole Blood-Based Endothelial Cell Impedance Assay for Assessing Clinical Transient Receptor Potential Vanilloid 4 Target Engagement Ex Vivo.

Xu X, Goyal N, Costell MH, Roethke T, James CH, Thorneloe KS, Patterson J, Stoy P, Goodman K, Sprecher DL, Behm DJ. Xu X, et al. Among authors: james ch. J Pharmacol Exp Ther. 2021 Mar;376(3):436-443. doi: 10.1124/jpet.120.000307. Epub 2020 Dec 29. J Pharmacol Exp Ther. 2021. PMID: 33376150

4

In Vitro Toxicity of Local Anesthetics and Corticosteroids on Chondrocyte and Synoviocyte Viability and Metabolism.

Sherman SL, Khazai RS, James CH, Stoker AM, Flood DL, Cook JL. Sherman SL, et al. Among authors: james ch. Cartilage. 2015 Oct;6(4):233-40. doi: 10.1177/1947603515594453. Cartilage. 2015. PMID: 26425261 Free PMC article.

5

Synthesis, anti-mycobacterial activity and DNA sequence-selectivity of a library of biaryl-motifs containing polyamides.

Brucoli F, Guzman JD, Maitra A, James CH, Fox KR, Bhakta S. Brucoli F, et al. Among authors: james ch. Bioorg Med Chem. 2015 Jul 1;23(13):3705-11. doi: 10.1016/j.bmc.2015.04.001. Epub 2015 Apr 8. Bioorg Med Chem. 2015. PMID: 25921267

6

Effect of hairpin loop structure on reactivity, sequence preference and adduct orientation of a DNA-interactive pyrrolo[2,1-c][1,4]benzodiazepine (PBD) antitumour agent.

Thurston DE, Vassoler H, Jackson PJ, James CH, Rahman KM. Thurston DE, et al. Among authors: james ch. Org Biomol Chem. 2015 Apr 7;13(13):4031-40. doi: 10.1039/c4ob02405b. Org Biomol Chem. 2015. PMID: 25733051

7

Human Leukocyte Antigen (HLA) A*1101-Restricted Epstein-Barr Virus-Specific T-cell Receptor Gene Transfer to Target Nasopharyngeal Carcinoma.

Zheng Y, Parsonage G, Zhuang X, Machado LR, James CH, Salman A, Searle PF, Hui EP, Chan AT, Lee SP. Zheng Y, et al. Among authors: james ch. Cancer Immunol Res. 2015 Oct;3(10):1138-47. doi: 10.1158/2326-6066.CIR-14-0203-T. Epub 2015 Feb 24. Cancer Immunol Res. 2015. PMID: 25711537 Free PMC article.

8

Computational studies support the role of the C7-sibirosamine sugar of the pyrrolobenzodiazepine (PBD) sibiromycin in transcription factor inhibition.

Jackson PJ, James CH, Jenkins TC, Rahman KM, Thurston DE. Jackson PJ, et al. Among authors: james ch. ACS Chem Biol. 2014 Oct 17;9(10):2432-40. doi: 10.1021/cb5002203. Epub 2014 Aug 11. ACS Chem Biol. 2014. PMID: 25111266

9

An extended pyrrolobenzodiazepine-polyamide conjugate with selectivity for a DNA sequence containing the ICB2 transcription factor binding site.

Brucoli F, Hawkins RM, James CH, Jackson PJ, Wells G, Jenkins TC, Ellis T, Kotecha M, Hochhauser D, Hartley JA, Howard PW, Thurston DE. Brucoli F, et al. Among authors: james ch. J Med Chem. 2013 Aug 22;56(16):6339-51. doi: 10.1021/jm4001852. Epub 2013 Jul 26. J Med Chem. 2013. PMID: 23889553

10

GC-targeted C8-linked pyrrolobenzodiazepine-biaryl conjugates with femtomolar in vitro cytotoxicity and in vivo antitumor activity in mouse models.

Rahman KM, Jackson PJ, James CH, Basu BP, Hartley JA, de la Fuente M, Schatzlein A, Robson M, Pedley RB, Pepper C, Fox KR, Howard PW, Thurston DE. Rahman KM, et al. Among authors: james ch. J Med Chem. 2013 Apr 11;56(7):2911-35. doi: 10.1021/jm301882a. Epub 2013 Mar 21. J Med Chem. 2013. PMID: 23514599

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