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Pharmacologic blockade of angiopoietin-2 is efficacious against model hemangiomas in mice.
Perry BN, Govindarajan B, Bhandarkar SS, Knaus UG, Valo M, Sturk C, Carrillo CO, Sohn A, Cerimele F, Dumont D, Losken A, Williams J, Brown LF, Tan X, Ioffe E, Yancopoulos GD, Arbiser JL. Perry BN, et al. Among authors: dumont d. J Invest Dermatol. 2006 Oct;126(10):2316-22. doi: 10.1038/sj.jid.5700413. Epub 2006 Jun 1. J Invest Dermatol. 2006. PMID: 16741507 Free article.
Tyrosine phosphorylation of Grb14 by Tie2.
Sturk C, Dumont DJ. Sturk C, et al. Cell Commun Signal. 2010 Oct 25;8:30. doi: 10.1186/1478-811X-8-30. Cell Commun Signal. 2010. PMID: 20973951 Free PMC article.
A negative regulatory role for Y1111 on the Tie-2 RTK.
Sturk C, Kim H, Jones N, Dumont DJ. Sturk C, et al. Among authors: dumont dj. Cell Signal. 2010 Apr;22(4):676-83. doi: 10.1016/j.cellsig.2009.12.002. Epub 2009 Dec 21. Cell Signal. 2010. PMID: 20026268
A cyclosporine-sensitive psoriasis-like disease produced in Tie2 transgenic mice.
Voskas D, Jones N, Van Slyke P, Sturk C, Chang W, Haninec A, Babichev YO, Tran J, Master Z, Chen S, Ward N, Cruz M, Jones J, Kerbel RS, Jothy S, Dagnino L, Arbiser J, Klement G, Dumont DJ. Voskas D, et al. Among authors: dumont dj. Am J Pathol. 2005 Mar;166(3):843-55. doi: 10.1016/S0002-9440(10)62305-X. Am J Pathol. 2005. PMID: 15743796 Free PMC article.
245 results