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Page 1
Effect of quinolinic acid on endogenous antioxidants in rat corpus striatum.
Rodríguez-Martínez E, Camacho A, Maldonado PD, Pedraza-Chaverrí J, Santamaría D, Galván-Arzate S, Santamaría A. Rodríguez-Martínez E, et al. Among authors: santamaria d, santamaria a. Brain Res. 2000 Mar 10;858(2):436-9. doi: 10.1016/s0006-8993(99)02474-9. Brain Res. 2000. PMID: 10708698
Experimental variables determine the outcome of RAS-RAS interactions.
Zhou Z, Nguyen TL, Li X, Poujol C, Berlinska E, Michelina SV, Kapp JN, Plückthun A, Winslow MM, Ambrogio C, Shan Y, Santamaría D, Westover KD. Zhou Z, et al. Among authors: santamaria d. J Biol Chem. 2024 Nov;300(11):107859. doi: 10.1016/j.jbc.2024.107859. Epub 2024 Oct 5. J Biol Chem. 2024. PMID: 39374781 Free PMC article.
RAS-ON inhibition overcomes clinical resistance to KRAS G12C-OFF covalent blockade.
Nokin MJ, Mira A, Patrucco E, Ricciuti B, Cousin S, Soubeyran I, San José S, Peirone S, Caizzi L, Vietti Michelina S, Bourdon A, Wang X, Alvarez-Villanueva D, Martínez-Iniesta M, Vidal A, Rodrigues T, García-Macías C, Awad MM, Nadal E, Villanueva A, Italiano A, Cereda M, Santamaría D, Ambrogio C. Nokin MJ, et al. Among authors: santamaria d. Nat Commun. 2024 Aug 30;15(1):7554. doi: 10.1038/s41467-024-51828-2. Nat Commun. 2024. PMID: 39215000 Free PMC article.
Type I interferon signaling pathway enhances immune-checkpoint inhibition in KRAS mutant lung tumors.
Fernández-García F, Fernández-Rodríguez A, Fustero-Torre C, Piñeiro-Yáñez E, Wang H, Lechuga CG, Callejas S, Álvarez R, López-García A, Esteban-Burgos L, Salmón M, San Román M, Guerra C, Ambrogio C, Drosten M, Santamaría D, Al-Shahrour F, Dopazo A, Barbacid M, Musteanu M. Fernández-García F, et al. Among authors: santamaria d. Proc Natl Acad Sci U S A. 2024 Sep 3;121(36):e2402913121. doi: 10.1073/pnas.2402913121. Epub 2024 Aug 26. Proc Natl Acad Sci U S A. 2024. PMID: 39186651
In vivo vulnerabilities to GPX4 and HDAC inhibitors in drug-persistent versus drug-resistant BRAFV600E lung adenocarcinoma.
Nokin MJ, Darbo E, Richard E, San José S, de Hita S, Prouzet-Mauleon V, Turcq B, Gerardelli L, Crake R, Velasco V, Koopmansch B, Lambert F, Xue JY, Sang B, Horne J, Ziemons E, Villanueva A, Blomme A, Herfs M, Cataldo D, Calvayrac O, Porporato P, Nadal E, Lito P, Jänne PA, Ricciuti B, Awad MM, Ambrogio C, Santamaría D; Bolero Consortium. Nokin MJ, et al. Among authors: santamaria d. Cell Rep Med. 2024 Aug 20;5(8):101663. doi: 10.1016/j.xcrm.2024.101663. Epub 2024 Aug 1. Cell Rep Med. 2024. PMID: 39094577 Free PMC article.
Concurrent inhibition of oncogenic and wild-type RAS-GTP for cancer therapy.
Holderfield M, Lee BJ, Jiang J, Tomlinson A, Seamon KJ, Mira A, Patrucco E, Goodhart G, Dilly J, Gindin Y, Dinglasan N, Wang Y, Lai LP, Cai S, Jiang L, Nasholm N, Shifrin N, Blaj C, Shah H, Evans JW, Montazer N, Lai O, Shi J, Ahler E, Quintana E, Chang S, Salvador A, Marquez A, Cregg J, Liu Y, Milin A, Chen A, Ziv TB, Parsons D, Knox JE, Klomp JE, Roth J, Rees M, Ronan M, Cuevas-Navarro A, Hu F, Lito P, Santamaria D, Aguirre AJ, Waters AM, Der CJ, Ambrogio C, Wang Z, Gill AL, Koltun ES, Smith JAM, Wildes D, Singh M. Holderfield M, et al. Among authors: santamaria d. Nature. 2024 May;629(8013):919-926. doi: 10.1038/s41586-024-07205-6. Epub 2024 Apr 8. Nature. 2024. PMID: 38589574 Free PMC article.
69 results