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A randomised trial to compare the pharmacokinetic, pharmacodynamic, and antiviral effects of peginterferon alfa-2b and peginterferon alfa-2a in patients with chronic hepatitis C (COMPARE).
Silva M, Poo J, Wagner F, Jackson M, Cutler D, Grace M, Bordens R, Cullen C, Harvey J, Laughlin M. Silva M, et al. Among authors: grace m. J Hepatol. 2006 Aug;45(2):204-13. doi: 10.1016/j.jhep.2006.03.008. Epub 2006 Apr 18. J Hepatol. 2006. PMID: 16780997 Clinical Trial.
Pegylated IFNs for chronic hepatitis C: an update.
Grace MJ, Cutler DL, Bordens RW. Grace MJ, et al. Expert Opin Drug Deliv. 2005 Mar;2(2):219-26. doi: 10.1517/17425247.2.2.219. Expert Opin Drug Deliv. 2005. PMID: 16296749 Review.
Site of pegylation and polyethylene glycol molecule size attenuate interferon-alpha antiviral and antiproliferative activities through the JAK/STAT signaling pathway.
Grace MJ, Lee S, Bradshaw S, Chapman J, Spond J, Cox S, Delorenzo M, Brassard D, Wylie D, Cannon-Carlson S, Cullen C, Indelicato S, Voloch M, Bordens R. Grace MJ, et al. J Biol Chem. 2005 Feb 25;280(8):6327-36. doi: 10.1074/jbc.M412134200. Epub 2004 Dec 13. J Biol Chem. 2005. PMID: 15596441 Free article.
998 results