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Enhanced PIP3 signaling in POMC neurons causes KATP channel activation and leads to diet-sensitive obesity.
Plum L, Ma X, Hampel B, Balthasar N, Coppari R, Münzberg H, Shanabrough M, Burdakov D, Rother E, Janoschek R, Alber J, Belgardt BF, Koch L, Seibler J, Schwenk F, Fekete C, Suzuki A, Mak TW, Krone W, Horvath TL, Ashcroft FM, Brüning JC. Plum L, et al. Among authors: belgardt bf. J Clin Invest. 2006 Jul;116(7):1886-901. doi: 10.1172/JCI27123. Epub 2006 Jun 22. J Clin Invest. 2006. PMID: 16794735 Free PMC article.
Central insulin action in energy and glucose homeostasis.
Plum L, Belgardt BF, Brüning JC. Plum L, et al. Among authors: belgardt bf. J Clin Invest. 2006 Jul;116(7):1761-6. doi: 10.1172/JCI29063. J Clin Invest. 2006. PMID: 16823473 Free PMC article. Review.
Hormone and glucose signalling in POMC and AgRP neurons.
Belgardt BF, Okamura T, Brüning JC. Belgardt BF, et al. J Physiol. 2009 Nov 15;587(Pt 22):5305-14. doi: 10.1113/jphysiol.2009.179192. Epub 2009 Sep 21. J Physiol. 2009. PMID: 19770186 Free PMC article. Review.
Novel roles for JNK1 in metabolism.
Belgardt BF, Mauer J, Brüning JC. Belgardt BF, et al. Aging (Albany NY). 2010 Sep;2(9):621-6. doi: 10.18632/aging.100192. Aging (Albany NY). 2010. PMID: 20834068 Free PMC article.
Distinct Roles for JNK and IKK Activation in Agouti-Related Peptide Neurons in the Development of Obesity and Insulin Resistance.
Tsaousidou E, Paeger L, Belgardt BF, Pal M, Wunderlich CM, Brönneke H, Collienne U, Hampel B, Wunderlich FT, Schmidt-Supprian M, Kloppenburg P, Brüning JC. Tsaousidou E, et al. Among authors: belgardt bf. Cell Rep. 2014 Nov 20;9(4):1495-506. doi: 10.1016/j.celrep.2014.10.045. Epub 2014 Nov 13. Cell Rep. 2014. PMID: 25456138 Free article.
37 results