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Page 1
CD52 is expressed on human mast cells and is a potential therapeutic target in Waldenstrom's Macroglobulinemia and mast cell disorders.
Santos DD, Hatjiharissi E, Tournilhac O, Chemaly MZ, Leleu X, Xu L, Patterson C, Branagan AR, Manning RJ, Ho AW, Hunter ZR, Dimmock EA, Kutok JL, Churchill WH, Castells MC, Tai YT, Anderson KC, Treon SP. Santos DD, et al. Among authors: dimmock ea. Clin Lymphoma Myeloma. 2006 May;6(6):478-83. doi: 10.3816/CLM.2006.n.029. Clin Lymphoma Myeloma. 2006. PMID: 16796779
Hepatitis C viral infection is not associated with Waldenström's macroglobulinemia.
Leleu X, O'Connor K, Ho AW, Santos DD, Manning R, Xu L, Hatjiharissi E, Moreau AS, Branagan AR, Hunter ZR, Dimmock EA, Soumerai J, Patterson C, Ghobrial I, Treon SP. Leleu X, et al. Among authors: dimmock ea. Am J Hematol. 2007 Jan;82(1):83-4. doi: 10.1002/ajh.20724. Am J Hematol. 2007. PMID: 16955461 Free article. Clinical Trial.
Increased natural killer cell expression of CD16, augmented binding and ADCC activity to rituximab among individuals expressing the Fc{gamma}RIIIa-158 V/V and V/F polymorphism.
Hatjiharissi E, Xu L, Santos DD, Hunter ZR, Ciccarelli BT, Verselis S, Modica M, Cao Y, Manning RJ, Leleu X, Dimmock EA, Kortsaris A, Mitsiades C, Anderson KC, Fox EA, Treon SP. Hatjiharissi E, et al. Among authors: dimmock ea. Blood. 2007 Oct 1;110(7):2561-4. doi: 10.1182/blood-2007-01-070656. Epub 2007 May 2. Blood. 2007. PMID: 17475906 Free PMC article.
Combination mammalian target of rapamycin inhibitor rapamycin and HSP90 inhibitor 17-allylamino-17-demethoxygeldanamycin has synergistic activity in multiple myeloma.
Francis LK, Alsayed Y, Leleu X, Jia X, Singha UK, Anderson J, Timm M, Ngo H, Lu G, Huston A, Ehrlich LA, Dimmock E, Lentzsch S, Hideshima T, Roodman GD, Anderson KC, Ghobrial IM. Francis LK, et al. Clin Cancer Res. 2006 Nov 15;12(22):6826-35. doi: 10.1158/1078-0432.CCR-06-1331. Clin Cancer Res. 2006. PMID: 17121904