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Method validation and preliminary qualification of pharmacodynamic biomarkers employed to evaluate the clinical efficacy of an antisense compound (AEG35156) targeted to the X-linked inhibitor of apoptosis protein XIAP.
Cummings J, Ranson M, Lacasse E, Ganganagari JR, St-Jean M, Jayson G, Durkin J, Dive C. Cummings J, et al. Among authors: ranson m. Br J Cancer. 2006 Jul 3;95(1):42-8. doi: 10.1038/sj.bjc.6603220. Br J Cancer. 2006. PMID: 16804528 Free PMC article.
Targeted antitumour therapy--future perspectives.
Ranson M, Jayson G. Ranson M, et al. Br J Cancer. 2005 Jun;92 Suppl 1(Suppl 1):S28-31. doi: 10.1038/sj.bjc.6602606. Br J Cancer. 2005. PMID: 15928656 Free PMC article.
Biomarker method validation in anticancer drug development.
Cummings J, Ward TH, Greystoke A, Ranson M, Dive C. Cummings J, et al. Among authors: ranson m. Br J Pharmacol. 2008 Feb;153(4):646-56. doi: 10.1038/sj.bjp.0707441. Epub 2007 Sep 17. Br J Pharmacol. 2008. PMID: 17876307 Free PMC article. Review.
Biomarkers of apoptosis.
Ward TH, Cummings J, Dean E, Greystoke A, Hou JM, Backen A, Ranson M, Dive C. Ward TH, et al. Among authors: ranson m. Br J Cancer. 2008 Sep 16;99(6):841-6. doi: 10.1038/sj.bjc.6604519. Br J Cancer. 2008. PMID: 19238626 Free PMC article. Review.
Apoptosis pathway-targeted drugs--from the bench to the clinic.
Cummings J, Ward TH, Ranson M, Dive C. Cummings J, et al. Among authors: ranson m. Biochim Biophys Acta. 2004 Dec 10;1705(1):53-66. doi: 10.1016/j.bbcan.2004.09.005. Biochim Biophys Acta. 2004. PMID: 15585173 Review.
353 results