Heim M - Search Results

1

Debrisoquine/sparteine hydroxylation genotype and phenotype: analysis of common mutations and alleles of CYP2D6 in a European population.

Broly F, Gaedigk A, Heim M, Eichelbaum M, Morike K, Meyer UA. Broly F, et al. Among authors: heim m. DNA Cell Biol. 1991 Oct;10(8):545-58. doi: 10.1089/dna.1991.10.545. DNA Cell Biol. 1991. PMID: 1681816

2

Genotyping of poor metabolisers of debrisoquine by allele-specific PCR amplification.

Heim M, Meyer UA. Heim M, et al. Lancet. 1990 Sep 1;336(8714):529-32. doi: 10.1016/0140-6736(90)92086-w. Lancet. 1990. PMID: 1975039

3

Multiple mutations of the human cytochrome P450IID6 gene (CYP2D6) in poor metabolizers of debrisoquine. Study of the functional significance of individual mutations by expression of chimeric genes.

Kagimoto M, Heim M, Kagimoto K, Zeugin T, Meyer UA. Kagimoto M, et al. Among authors: heim m. J Biol Chem. 1990 Oct 5;265(28):17209-14. J Biol Chem. 1990. PMID: 2211621 Free article.

4

Evolution of a highly polymorphic human cytochrome P450 gene cluster: CYP2D6.

Heim MH, Meyer UA. Heim MH, et al. Genomics. 1992 Sep;14(1):49-58. doi: 10.1016/s0888-7543(05)80282-4. Genomics. 1992. PMID: 1358797

5

Predicting debrisoquine phenotype.

Heim M, Meyer UA. Heim M, et al. Lancet. 1991 Feb 9;337(8737):363. doi: 10.1016/0140-6736(91)90991-w. Lancet. 1991. PMID: 1671255 No abstract available.

6

Molecular mechanism of slow acetylation of drugs and carcinogens in humans.

Blum M, Demierre A, Grant DM, Heim M, Meyer UA. Blum M, et al. Among authors: heim m. Proc Natl Acad Sci U S A. 1991 Jun 15;88(12):5237-41. doi: 10.1073/pnas.88.12.5237. Proc Natl Acad Sci U S A. 1991. PMID: 1675794 Free PMC article.

7

Human arylamine N-acetyltransferase genes: isolation, chromosomal localization, and functional expression.

Blum M, Grant DM, McBride W, Heim M, Meyer UA. Blum M, et al. Among authors: heim m. DNA Cell Biol. 1990 Apr;9(3):193-203. doi: 10.1089/dna.1990.9.193. DNA Cell Biol. 1990. PMID: 2340091

8

Genetic polymorphism of debrisoquine oxidation: restriction fragment analysis and allele-specific amplification of mutant alleles of CYP2D6.

Heim MH, Meyer UA. Heim MH, et al. Methods Enzymol. 1991;206:173-83. doi: 10.1016/0076-6879(91)06088-k. Methods Enzymol. 1991. PMID: 1686063 No abstract available.

9

Genetic analysis of the interethnic difference between Chinese and Caucasians in the polymorphic metabolism of debrisoquine and codeine.

Johansson I, Yue QY, Dahl ML, Heim M, Säwe J, Bertilsson L, Meyer UA, Sjöqvist F, Ingelman-Sundberg M. Johansson I, et al. Among authors: heim m. Eur J Clin Pharmacol. 1991;40(6):553-6. doi: 10.1007/BF00279968. Eur J Clin Pharmacol. 1991. PMID: 1679392

10

Nucleotide sequence of rabbit NAT1 encoding monomorphic arylamine N-acetyltransferase.

Blum M, Heim M, Meyer UA. Blum M, et al. Among authors: heim m. Nucleic Acids Res. 1990 Sep 11;18(17):5287. doi: 10.1093/nar/18.17.5287. Nucleic Acids Res. 1990. PMID: 2402454 Free PMC article. No abstract available.

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