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Benzodiazepine Scaffold as Drug-like Molecular Simplification of FR235222: A Chemical Tool for Exploring HDAC Inhibition.
Randino R, Moronese I, Cini E, Bizzarro V, Persico M, Grimaldi M, Scrima M, D'Ursi AM, Novellino E, Sobarzo-Sanchez E, Rastrelli L, Fattorusso C, Petrella A, Rodriquez M, Taddei M. Randino R, et al. Among authors: rodriquez m. Curr Top Med Chem. 2017;17(4):441-459. doi: 10.2174/1568026616666160824105645. Curr Top Med Chem. 2017. PMID: 27558677
Discovery and Optimization of Indoline-Based Compounds as Dual 5-LOX/sEH Inhibitors: In Vitro and In Vivo Anti-Inflammatory Characterization.
Cerqua I, Musella S, Peltner LK, D'Avino D, Di Sarno V, Granato E, Vestuto V, Di Matteo R, Pace S, Ciaglia T, Bilancia R, Smaldone G, Di Matteo F, Di Micco S, Bifulco G, Pepe G, Basilicata MG, Rodriquez M, Gomez-Monterrey IM, Campiglia P, Ostacolo C, Roviezzo F, Werz O, Rossi A, Bertamino A. Cerqua I, et al. Among authors: rodriquez m. J Med Chem. 2022 Nov 10;65(21):14456-14480. doi: 10.1021/acs.jmedchem.2c00817. Epub 2022 Nov 1. J Med Chem. 2022. PMID: 36318728 Free PMC article.
Specific targeting highly conserved residues in the HIV-1 reverse transcriptase primer grip region. Design, synthesis, and biological evaluation of novel, potent, and broad spectrum NNRTIs with antiviral activity.
Fattorusso C, Gemma S, Butini S, Huleatt P, Catalanotti B, Persico M, De Angelis M, Fiorini I, Nacci V, Ramunno A, Rodriquez M, Greco G, Novellino E, Bergamini A, Marini S, Coletta M, Maga G, Spadari S, Campiani G. Fattorusso C, et al. Among authors: rodriquez m. J Med Chem. 2005 Nov 17;48(23):7153-65. doi: 10.1021/jm050257d. J Med Chem. 2005. PMID: 16279773
131 results