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Definable equilibrium states in the folding of human prion protein.
Hosszu LL, Wells MA, Jackson GS, Jones S, Batchelor M, Clarke AR, Craven CJ, Waltho JP, Collinge J. Hosszu LL, et al. Among authors: clarke ar. Biochemistry. 2005 Dec 20;44(50):16649-57. doi: 10.1021/bi051277k. Biochemistry. 2005. PMID: 16342955
Elongated oligomers assemble into mammalian PrP amyloid fibrils.
Tattum MH, Cohen-Krausz S, Thumanu K, Wharton CW, Khalili-Shirazi A, Jackson GS, Orlova EV, Collinge J, Clarke AR, Saibil HR. Tattum MH, et al. Among authors: clarke ar. J Mol Biol. 2006 Mar 31;357(3):975-85. doi: 10.1016/j.jmb.2006.01.052. Epub 2006 Jan 31. J Mol Biol. 2006. PMID: 16473369
Folding kinetics of the human prion protein probed by temperature jump.
Hart T, Hosszu LL, Trevitt CR, Jackson GS, Waltho JP, Collinge J, Clarke AR. Hart T, et al. Among authors: clarke ar. Proc Natl Acad Sci U S A. 2009 Apr 7;106(14):5651-6. doi: 10.1073/pnas.0811457106. Epub 2009 Mar 24. Proc Natl Acad Sci U S A. 2009. PMID: 19321423 Free PMC article.
Pharmacological chaperone for the structured domain of human prion protein.
Nicoll AJ, Trevitt CR, Tattum MH, Risse E, Quarterman E, Ibarra AA, Wright C, Jackson GS, Sessions RB, Farrow M, Waltho JP, Clarke AR, Collinge J. Nicoll AJ, et al. Among authors: clarke ar. Proc Natl Acad Sci U S A. 2010 Oct 12;107(41):17610-5. doi: 10.1073/pnas.1009062107. Epub 2010 Sep 27. Proc Natl Acad Sci U S A. 2010. PMID: 20876144 Free PMC article.
A systematic investigation of production of synthetic prions from recombinant prion protein.
Schmidt C, Fizet J, Properzi F, Batchelor M, Sandberg MK, Edgeworth JA, Afran L, Ho S, Badhan A, Klier S, Linehan JM, Brandner S, Hosszu LL, Tattum MH, Jat P, Clarke AR, Klöhn PC, Wadsworth JD, Jackson GS, Collinge J. Schmidt C, et al. Among authors: clarke ar. Open Biol. 2015 Dec;5(12):150165. doi: 10.1098/rsob.150165. Open Biol. 2015. PMID: 26631378 Free PMC article.
562 results