Moras D - Search Results

1

Ligand binding domain of vitamin D receptors.

Rochel N, Moras D. Rochel N, et al. Among authors: moras d. Curr Top Med Chem. 2006;6(12):1229-41. doi: 10.2174/156802606777864926. Curr Top Med Chem. 2006. PMID: 16848737 Review.

2

Structural adaptability in the ligand-binding pocket of the ecdysone hormone receptor.

Billas IM, Iwema T, Garnier JM, Mitschler A, Rochel N, Moras D. Billas IM, et al. Among authors: moras d. Nature. 2003 Nov 6;426(6962):91-6. doi: 10.1038/nature02112. Epub 2003 Nov 2. Nature. 2003. PMID: 14595375

3

Crystal structures of the vitamin D nuclear receptor liganded with the vitamin D side chain analogues calcipotriol and seocalcitol, receptor agonists of clinical importance. Insights into a structural basis for the switching of calcipotriol to a receptor antagonist by further side chain modification.

Tocchini-Valentini G, Rochel N, Wurtz JM, Moras D. Tocchini-Valentini G, et al. Among authors: moras d. J Med Chem. 2004 Apr 8;47(8):1956-61. doi: 10.1021/jm0310582. J Med Chem. 2004. PMID: 15055995

4

Structural investigation of the ligand binding domain of the zebrafish VDR in complexes with 1alpha,25(OH)2D3 and Gemini: purification, crystallization and preliminary X-ray diffraction analysis.

Ciesielski F, Rochel N, Mitschler A, Kouzmenko A, Moras D. Ciesielski F, et al. Among authors: moras d. J Steroid Biochem Mol Biol. 2004 May;89-90(1-5):55-9. doi: 10.1016/j.jsbmb.2004.03.109. J Steroid Biochem Mol Biol. 2004. PMID: 15225747

5

RARbeta ligand-binding domain bound to an SRC-1 co-activator peptide: purification, crystallization and preliminary X-ray diffraction analysis.

Kammerer S, Germain P, Flaig R, Peluso-Iltis C, Mitschler A, Rochel N, Gronemeyer H, Moras D. Kammerer S, et al. Among authors: moras d. Acta Crystallogr D Biol Crystallogr. 2004 Nov;60(Pt 11):2048-50. doi: 10.1107/S0907444904021201. Epub 2004 Oct 20. Acta Crystallogr D Biol Crystallogr. 2004. PMID: 15502323

6

Novel 1alpha,25-dihydroxyvitamin D3 analogues with the side chain at C12.

González-Avión XC, Mouriño A, Rochel N, Moras D. González-Avión XC, et al. Among authors: moras d. J Med Chem. 2006 Mar 9;49(5):1509-16. doi: 10.1021/jm049016g. J Med Chem. 2006. PMID: 16509569

7

Probing a water channel near the A-ring of receptor-bound 1 alpha,25-dihydroxyvitamin D3 with selected 2 alpha-substituted analogues.

Hourai S, Fujishima T, Kittaka A, Suhara Y, Takayama H, Rochel N, Moras D. Hourai S, et al. Among authors: moras d. J Med Chem. 2006 Aug 24;49(17):5199-205. doi: 10.1021/jm0604070. J Med Chem. 2006. PMID: 16913708

8

Adaptability of the Vitamin D nuclear receptor to the synthetic ligand Gemini: remodelling the LBP with one side chain rotation.

Ciesielski F, Rochel N, Moras D. Ciesielski F, et al. Among authors: moras d. J Steroid Biochem Mol Biol. 2007 Mar;103(3-5):235-42. doi: 10.1016/j.jsbmb.2006.12.003. Epub 2007 Jan 10. J Steroid Biochem Mol Biol. 2007. PMID: 17218092

9

Crystal structure of the vitamin D nuclear receptor ligand binding domain in complex with a locked side chain analog of calcitriol.

Rochel N, Hourai S, Pérez-García X, Rumbo A, Mourino A, Moras D. Rochel N, et al. Among authors: moras d. Arch Biochem Biophys. 2007 Apr 15;460(2):172-6. doi: 10.1016/j.abb.2007.01.031. Epub 2007 Feb 20. Arch Biochem Biophys. 2007. PMID: 17346665

10

Structure-based design of a superagonist ligand for the vitamin D nuclear receptor.

Hourai S, Rodrigues LC, Antony P, Reina-San-Martin B, Ciesielski F, Magnier BC, Schoonjans K, Mouriño A, Rochel N, Moras D. Hourai S, et al. Among authors: moras d. Chem Biol. 2008 Apr;15(4):383-92. doi: 10.1016/j.chembiol.2008.03.016. Chem Biol. 2008. PMID: 18420145

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