Krishnan S - Search Results

1

Differentiation and quantitative determination of surface and hydrate water in lyophilized mannitol using NIR spectroscopy.

Cao W, Mao C, Chen W, Lin H, Krishnan S, Cauchon N. Cao W, et al. Among authors: krishnan s. J Pharm Sci. 2006 Sep;95(9):2077-86. doi: 10.1002/jps.20706. J Pharm Sci. 2006. PMID: 16850397

2

Influence of process conditions on the crystallization and transition of metastable mannitol forms in protein formulations during lyophilization.

Cao W, Xie Y, Krishnan S, Lin H, Ricci M. Cao W, et al. Among authors: krishnan s. Pharm Res. 2013 Jan;30(1):131-9. doi: 10.1007/s11095-012-0855-9. Epub 2012 Aug 21. Pharm Res. 2013. PMID: 22907420

3

Characterization of mannitol polymorphic forms in lyophilized protein formulations using a multivariate curve resolution (MCR)-based Raman spectroscopic method.

Xie Y, Cao W, Krishnan S, Lin H, Cauchon N. Xie Y, et al. Among authors: krishnan s. Pharm Res. 2008 Oct;25(10):2292-301. doi: 10.1007/s11095-008-9624-1. Epub 2008 Jun 4. Pharm Res. 2008. PMID: 18523875

4

Rational design of lyophilized high concentration protein formulations-mitigating the challenge of slow reconstitution with multidisciplinary strategies.

Cao W, Krishnan S, Ricci MS, Shih LY, Liu D, Gu JH, Jameel F. Cao W, et al. Among authors: krishnan s. Eur J Pharm Biopharm. 2013 Oct;85(2):287-93. doi: 10.1016/j.ejpb.2013.05.001. Epub 2013 May 20. Eur J Pharm Biopharm. 2013. PMID: 23702275

5

Effect of pH and excipients on structure, dynamics, and long-term stability of a model IgG1 monoclonal antibody upon freeze-drying.

Park J, Nagapudi K, Vergara C, Ramachander R, Laurence JS, Krishnan S. Park J, et al. Among authors: krishnan s. Pharm Res. 2013 Apr;30(4):968-84. doi: 10.1007/s11095-012-0933-z. Epub 2012 Nov 27. Pharm Res. 2013. PMID: 23184227

6

Active dimer of Epratuzumab provides insight into the complex nature of an antibody aggregate.

Remmele RL Jr, Callahan WJ, Krishnan S, Zhou L, Bondarenko PV, Nichols AC, Kleemann GR, Pipes GD, Park S, Fodor S, Kras E, Brems DN. Remmele RL Jr, et al. Among authors: krishnan s. J Pharm Sci. 2006 Jan;95(1):126-45. doi: 10.1002/jps.20515. J Pharm Sci. 2006. PMID: 16315222

7

Silicone oil- and agitation-induced aggregation of a monoclonal antibody in aqueous solution.

Thirumangalathu R, Krishnan S, Ricci MS, Brems DN, Randolph TW, Carpenter JF. Thirumangalathu R, et al. Among authors: krishnan s. J Pharm Sci. 2009 Sep;98(9):3167-81. doi: 10.1002/jps.21719. J Pharm Sci. 2009. PMID: 19360857 Free PMC article.

8

Optimizing storage stability of lyophilized recombinant human interleukin-11 with disaccharide/hydroxyethyl starch mixtures.

Garzon-Rodriguez W, Koval RL, Chongprasert S, Krishnan S, Randolph TW, Warne NW, Carpenter JF. Garzon-Rodriguez W, et al. Among authors: krishnan s. J Pharm Sci. 2004 Mar;93(3):684-96. doi: 10.1002/jps.10587. J Pharm Sci. 2004. PMID: 14762907

9

Development of stable lyophilized protein drug products.

Remmele RL, Krishnan S, Callahan WJ. Remmele RL, et al. Among authors: krishnan s. Curr Pharm Biotechnol. 2012 Mar;13(3):471-96. doi: 10.2174/138920112799361990. Curr Pharm Biotechnol. 2012. PMID: 22283723 Review.

10

Elucidation of degradants in acidic peak of cation exchange chromatography in an IgG1 monoclonal antibody formed on long-term storage in a liquid formulation.

Gandhi S, Ren D, Xiao G, Bondarenko P, Sloey C, Ricci MS, Krishnan S. Gandhi S, et al. Among authors: krishnan s. Pharm Res. 2012 Jan;29(1):209-24. doi: 10.1007/s11095-011-0536-0. Epub 2011 Aug 16. Pharm Res. 2012. PMID: 21845507

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