Shokat KM - Search Results

1

To stabilize neutrophil polarity, PIP3 and Cdc42 augment RhoA activity at the back as well as signals at the front.

Van Keymeulen A, Wong K, Knight ZA, Govaerts C, Hahn KM, Shokat KM, Bourne HR. Van Keymeulen A, et al. Among authors: shokat km. J Cell Biol. 2006 Jul 31;174(3):437-45. doi: 10.1083/jcb.200604113. Epub 2006 Jul 24. J Cell Biol. 2006. PMID: 16864657 Free PMC article.

2

The emerging power of chemical genetics.

Specht KM, Shokat KM. Specht KM, et al. Among authors: shokat km. Curr Opin Cell Biol. 2002 Apr;14(2):155-9. doi: 10.1016/s0955-0674(02)00317-4. Curr Opin Cell Biol. 2002. PMID: 11891113 Review.

3

The Saccharomyces cerevisiae Mob2p-Cbk1p kinase complex promotes polarized growth and acts with the mitotic exit network to facilitate daughter cell-specific localization of Ace2p transcription factor.

Weiss EL, Kurischko C, Zhang C, Shokat K, Drubin DG, Luca FC. Weiss EL, et al. J Cell Biol. 2002 Sep 2;158(5):885-900. doi: 10.1083/jcb.200203094. Epub 2002 Aug 26. J Cell Biol. 2002. PMID: 12196508 Free PMC article.

4

Phosphospecific proteolysis for mapping sites of protein phosphorylation.

Knight ZA, Schilling B, Row RH, Kenski DM, Gibson BW, Shokat KM. Knight ZA, et al. Among authors: shokat km. Nat Biotechnol. 2003 Sep;21(9):1047-54. doi: 10.1038/nbt863. Epub 2003 Aug 17. Nat Biotechnol. 2003. PMID: 12923550

5

Isoform-specific phosphoinositide 3-kinase inhibitors from an arylmorpholine scaffold.

Knight ZA, Chiang GG, Alaimo PJ, Kenski DM, Ho CB, Coan K, Abraham RT, Shokat KM. Knight ZA, et al. Among authors: shokat km. Bioorg Med Chem. 2004 Sep 1;12(17):4749-59. doi: 10.1016/j.bmc.2004.06.022. Bioorg Med Chem. 2004. PMID: 15358300

6

Targeting the gatekeeper residue in phosphoinositide 3-kinases.

Alaimo PJ, Knight ZA, Shokat KM. Alaimo PJ, et al. Among authors: shokat km. Bioorg Med Chem. 2005 Apr 15;13(8):2825-36. doi: 10.1016/j.bmc.2005.02.021. Bioorg Med Chem. 2005. PMID: 15781393

7

Features of selective kinase inhibitors.

Knight ZA, Shokat KM. Knight ZA, et al. Among authors: shokat km. Chem Biol. 2005 Jun;12(6):621-37. doi: 10.1016/j.chembiol.2005.04.011. Chem Biol. 2005. PMID: 15975507 Review.

8

A pharmacological map of the PI3-K family defines a role for p110alpha in insulin signaling.

Knight ZA, Gonzalez B, Feldman ME, Zunder ER, Goldenberg DD, Williams O, Loewith R, Stokoe D, Balla A, Toth B, Balla T, Weiss WA, Williams RL, Shokat KM. Knight ZA, et al. Among authors: shokat km. Cell. 2006 May 19;125(4):733-47. doi: 10.1016/j.cell.2006.03.035. Epub 2006 Apr 27. Cell. 2006. PMID: 16647110 Free PMC article.

9

Effect of combined DNA repair inhibition and G2 checkpoint inhibition on cell cycle progression after DNA damage.

Sturgeon CM, Knight ZA, Shokat KM, Roberge M. Sturgeon CM, et al. Among authors: shokat km. Mol Cancer Ther. 2006 Apr;5(4):885-92. doi: 10.1158/1535-7163.MCT-05-0358. Mol Cancer Ther. 2006. PMID: 16648558

10

A dual PI3 kinase/mTOR inhibitor reveals emergent efficacy in glioma.

Fan QW, Knight ZA, Goldenberg DD, Yu W, Mostov KE, Stokoe D, Shokat KM, Weiss WA. Fan QW, et al. Among authors: shokat km. Cancer Cell. 2006 May;9(5):341-9. doi: 10.1016/j.ccr.2006.03.029. Cancer Cell. 2006. PMID: 16697955 Free PMC article.

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