Wong K - Search Results

1

To stabilize neutrophil polarity, PIP3 and Cdc42 augment RhoA activity at the back as well as signals at the front.

Van Keymeulen A, Wong K, Knight ZA, Govaerts C, Hahn KM, Shokat KM, Bourne HR. Van Keymeulen A, et al. Among authors: wong k. J Cell Biol. 2006 Jul 31;174(3):437-45. doi: 10.1083/jcb.200604113. Epub 2006 Jul 24. J Cell Biol. 2006. PMID: 16864657 Free PMC article.

2

Neutrophil polarization: spatiotemporal dynamics of RhoA activity support a self-organizing mechanism.

Wong K, Pertz O, Hahn K, Bourne H. Wong K, et al. Proc Natl Acad Sci U S A. 2006 Mar 7;103(10):3639-44. doi: 10.1073/pnas.0600092103. Epub 2006 Feb 28. Proc Natl Acad Sci U S A. 2006. PMID: 16537448 Free PMC article.

3

Morphology matters in immune cell chemotaxis: membrane asymmetry affects amplification.

Onsum MD, Wong K, Herzmark P, Bourne HR, Arkin AP. Onsum MD, et al. Among authors: wong k. Phys Biol. 2006 Sep 25;3(3):190-9. doi: 10.1088/1478-3975/3/3/004. Phys Biol. 2006. PMID: 17021383

4

Formation of cysts by alveolar type II cells in three-dimensional culture reveals a novel mechanism for epithelial morphogenesis.

Yu W, Fang X, Ewald A, Wong K, Hunt CA, Werb Z, Matthay MA, Mostov K. Yu W, et al. Among authors: wong k. Mol Biol Cell. 2007 May;18(5):1693-700. doi: 10.1091/mbc.e06-11-1052. Epub 2007 Mar 1. Mol Biol Cell. 2007. PMID: 17332496 Free PMC article.

5

Bound attractant at the leading vs. the trailing edge determines chemotactic prowess.

Herzmark P, Campbell K, Wang F, Wong K, El-Samad H, Groisman A, Bourne HR. Herzmark P, et al. Among authors: wong k. Proc Natl Acad Sci U S A. 2007 Aug 14;104(33):13349-54. doi: 10.1073/pnas.0705889104. Epub 2007 Aug 7. Proc Natl Acad Sci U S A. 2007. PMID: 17684096 Free PMC article.

6

PDZRhoGEF and myosin II localize RhoA activity to the back of polarizing neutrophil-like cells.

Wong K, Van Keymeulen A, Bourne HR. Wong K, et al. J Cell Biol. 2007 Dec 17;179(6):1141-8. doi: 10.1083/jcb.200706167. J Cell Biol. 2007. PMID: 18086913 Free PMC article.

7

Phosphatidylserine receptor Tim-4 is essential for the maintenance of the homeostatic state of resident peritoneal macrophages.

Wong K, Valdez PA, Tan C, Yeh S, Hongo JA, Ouyang W. Wong K, et al. Proc Natl Acad Sci U S A. 2010 May 11;107(19):8712-7. doi: 10.1073/pnas.0910929107. Epub 2010 Apr 26. Proc Natl Acad Sci U S A. 2010. PMID: 20421466 Free PMC article.

8

IL-22 bridges the lymphotoxin pathway with the maintenance of colonic lymphoid structures during infection with Citrobacter rodentium.

Ota N, Wong K, Valdez PA, Zheng Y, Crellin NK, Diehl L, Ouyang W. Ota N, et al. Among authors: wong k. Nat Immunol. 2011 Aug 28;12(10):941-8. doi: 10.1038/ni.2089. Nat Immunol. 2011. PMID: 21874025

9

Targeting IL-10 Family Cytokines for the Treatment of Human Diseases.

Wang X, Wong K, Ouyang W, Rutz S. Wang X, et al. Among authors: wong k. Cold Spring Harb Perspect Biol. 2019 Feb 1;11(2):a028548. doi: 10.1101/cshperspect.a028548. Cold Spring Harb Perspect Biol. 2019. PMID: 29038121 Free PMC article. Review.

10

A randomized, placebo-controlled trial evaluating effects of lebrikizumab on airway eosinophilic inflammation and remodelling in uncontrolled asthma (CLAVIER).

Austin CD, Gonzalez Edick M, Ferrando RE, Solon M, Baca M, Mesh K, Bradding P, Gauvreau GM, Sumino K, FitzGerald JM, Israel E, Bjermer L, Bourdin A, Arron JR, Choy DF, Olsson JK, Abreu F, Howard M, Wong K, Cai F, Peng K, Putnam WS, Holweg CTJ, Matthews JG, Kraft M, Woodruff PG; CLAVIER Investigators. Austin CD, et al. Among authors: wong k. Clin Exp Allergy. 2020 Dec;50(12):1342-1351. doi: 10.1111/cea.13731. Epub 2020 Oct 4. Clin Exp Allergy. 2020. PMID: 32909660 Free PMC article. Clinical Trial.

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