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Granuphilin is activated by SREBP-1c and involved in impaired insulin secretion in diabetic mice.
Kato T, Shimano H, Yamamoto T, Yokoo T, Endo Y, Ishikawa M, Matsuzaka T, Nakagawa Y, Kumadaki S, Yahagi N, Takahashi A, Sone H, Suzuki H, Toyoshima H, Hasty AH, Takahashi S, Gomi H, Izumi T, Yamada N. Kato T, et al. Among authors: takahashi a, takahashi s. Cell Metab. 2006 Aug;4(2):143-54. doi: 10.1016/j.cmet.2006.06.009. Cell Metab. 2006. PMID: 16890542 Free article.
MafA is a key regulator of glucose-stimulated insulin secretion.
Zhang C, Moriguchi T, Kajihara M, Esaki R, Harada A, Shimohata H, Oishi H, Hamada M, Morito N, Hasegawa K, Kudo T, Engel JD, Yamamoto M, Takahashi S. Zhang C, et al. Among authors: takahashi s. Mol Cell Biol. 2005 Jun;25(12):4969-76. doi: 10.1128/MCB.25.12.4969-4976.2005. Mol Cell Biol. 2005. PMID: 15923615 Free PMC article.
Inhibition of ubiquitin ligase F-box and WD repeat domain-containing 7α (Fbw7α) causes hepatosteatosis through Krüppel-like factor 5 (KLF5)/peroxisome proliferator-activated receptor γ2 (PPARγ2) pathway but not SREBP-1c protein in mice.
Kumadaki S, Karasawa T, Matsuzaka T, Ema M, Nakagawa Y, Nakakuki M, Saito R, Yahagi N, Iwasaki H, Sone H, Takekoshi K, Yatoh S, Kobayashi K, Takahashi A, Suzuki H, Takahashi S, Yamada N, Shimano H. Kumadaki S, et al. Among authors: takahashi a, takahashi s. J Biol Chem. 2011 Nov 25;286(47):40835-46. doi: 10.1074/jbc.M111.235283. Epub 2011 Sep 12. J Biol Chem. 2011. PMID: 21911492 Free PMC article.
MafB promotes atherosclerosis by inhibiting foam-cell apoptosis.
Hamada M, Nakamura M, Tran MT, Moriguchi T, Hong C, Ohsumi T, Dinh TT, Kusakabe M, Hattori M, Katsumata T, Arai S, Nakashima K, Kudo T, Kuroda E, Wu CH, Kao PH, Sakai M, Shimano H, Miyazaki T, Tontonoz P, Takahashi S. Hamada M, et al. Among authors: takahashi s. Nat Commun. 2014;5:3147. doi: 10.1038/ncomms4147. Nat Commun. 2014. PMID: 24445679 Free article.
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