Kotnik M - Search Results

1

Flavonoids and cinnamic acid esters as inhibitors of fungal 17beta-hydroxysteroid dehydrogenase: a synthesis, QSAR and modelling study.

Sova M, Perdih A, Kotnik M, Kristan K, Rizner TL, Solmajer T, Gobec S. Sova M, et al. Among authors: kotnik m. Bioorg Med Chem. 2006 Nov 15;14(22):7404-18. doi: 10.1016/j.bmc.2006.07.027. Epub 2006 Aug 7. Bioorg Med Chem. 2006. PMID: 16891119

2

Novel naphthalene-N-sulfonyl-D-glutamic acid derivatives as inhibitors of MurD, a key peptidoglycan biosynthesis enzyme.

Humljan J, Kotnik M, Contreras-Martel C, Blanot D, Urleb U, Dessen A, Solmajer T, Gobec S. Humljan J, et al. Among authors: kotnik m. J Med Chem. 2008 Dec 11;51(23):7486-94. doi: 10.1021/jm800762u. J Med Chem. 2008. PMID: 19007109

3

Targeted molecular dynamics simulation studies of binding and conformational changes in E. coli MurD.

Perdih A, Kotnik M, Hodoscek M, Solmajer T. Perdih A, et al. Among authors: kotnik m. Proteins. 2007 Jul 1;68(1):243-54. doi: 10.1002/prot.21374. Proteins. 2007. PMID: 17427948

4

Structural and functional characterization of enantiomeric glutamic acid derivatives as potential transition state analogue inhibitors of MurD ligase.

Kotnik M, Humljan J, Contreras-Martel C, Oblak M, Kristan K, Hervé M, Blanot D, Urleb U, Gobec S, Dessen A, Solmajer T. Kotnik M, et al. J Mol Biol. 2007 Jun 29;370(1):107-15. doi: 10.1016/j.jmb.2007.04.048. Epub 2007 May 4. J Mol Biol. 2007. PMID: 17507028

5

Discovery and development of ATPase inhibitors of DNA gyrase as antibacterial agents.

Oblak M, Kotnik M, Solmajer T. Oblak M, et al. Among authors: kotnik m. Curr Med Chem. 2007;14(19):2033-47. doi: 10.2174/092986707781368414. Curr Med Chem. 2007. PMID: 17691945 Review.

6

Biophysical characterization of an indolinone inhibitor in the ATP-binding site of DNA gyrase.

Oblak M, Grdadolnik SG, Kotnik M, Poterszman A, Atkinson RA, Nierengarten H, Desplancq D, Moras D, Solmajer T. Oblak M, et al. Among authors: kotnik m. Biochem Biophys Res Commun. 2006 Nov 3;349(4):1206-13. doi: 10.1016/j.bbrc.2006.08.172. Epub 2006 Sep 7. Biochem Biophys Res Commun. 2006. PMID: 16979583

7

Enzyme binding selectivity prediction: alpha-thrombin vs trypsin inhibition.

Mlinsek G, Novic M, Kotnik M, Solmajer T. Mlinsek G, et al. Among authors: kotnik m. J Chem Inf Comput Sci. 2004 Sep-Oct;44(5):1872-82. doi: 10.1021/ci0401017. J Chem Inf Comput Sci. 2004. PMID: 15446847

8

New high-throughput fluorimetric assay for discovering inhibitors of UDP-N-acetylmuramyl-L-alanine: D-glutamate (MurD) ligase.

Kristan K, Kotnik M, Oblak M, Urleb U. Kristan K, et al. Among authors: kotnik m. J Biomol Screen. 2009 Apr;14(4):412-8. doi: 10.1177/1087057109332597. J Biomol Screen. 2009. PMID: 19403924

9

Crystallographic Study of Peptidoglycan Biosynthesis Enzyme MurD: Domain Movement Revisited.

Šink R, Kotnik M, Zega A, Barreteau H, Gobec S, Blanot D, Dessen A, Contreras-Martel C. Šink R, et al. Among authors: kotnik m. PLoS One. 2016 Mar 31;11(3):e0152075. doi: 10.1371/journal.pone.0152075. eCollection 2016. PLoS One. 2016. PMID: 27031227 Free PMC article.

10

In silico fragment-based discovery of indolin-2-one analogues as potent DNA gyrase inhibitors.

Oblak M, Grdadolnik SG, Kotnik M, Jerala R, Filipic M, Solmajer T. Oblak M, et al. Among authors: kotnik m. Bioorg Med Chem Lett. 2005 Dec 1;15(23):5207-10. doi: 10.1016/j.bmcl.2005.08.068. Epub 2005 Oct 3. Bioorg Med Chem Lett. 2005. PMID: 16203145

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