Leder P - Search Results

1

Mitochondriotoxic compounds for cancer therapy.

Fantin VR, Leder P. Fantin VR, et al. Among authors: leder p. Oncogene. 2006 Aug 7;25(34):4787-97. doi: 10.1038/sj.onc.1209599. Oncogene. 2006. PMID: 16892091 Review.

2

A novel mitochondriotoxic small molecule that selectively inhibits tumor cell growth.

Fantin VR, Berardi MJ, Scorrano L, Korsmeyer SJ, Leder P. Fantin VR, et al. Among authors: leder p. Cancer Cell. 2002 Jul;2(1):29-42. doi: 10.1016/s1535-6108(02)00082-x. Cancer Cell. 2002. PMID: 12150823 Free article.

3

F16, a mitochondriotoxic compound, triggers apoptosis or necrosis depending on the genetic background of the target carcinoma cell.

Fantin VR, Leder P. Fantin VR, et al. Among authors: leder p. Cancer Res. 2004 Jan 1;64(1):329-36. doi: 10.1158/0008-5472.can-03-0899. Cancer Res. 2004. PMID: 14729642

4

A bifunctional targeted peptide that blocks HER-2 tyrosine kinase and disables mitochondrial function in HER-2-positive carcinoma cells.

Fantin VR, Berardi MJ, Babbe H, Michelman MV, Manning CM, Leder P. Fantin VR, et al. Among authors: leder p. Cancer Res. 2005 Aug 1;65(15):6891-900. doi: 10.1158/0008-5472.CAN-05-0395. Cancer Res. 2005. PMID: 16061673

5

Attenuation of LDH-A expression uncovers a link between glycolysis, mitochondrial physiology, and tumor maintenance.

Fantin VR, St-Pierre J, Leder P. Fantin VR, et al. Among authors: leder p. Cancer Cell. 2006 Jun;9(6):425-34. doi: 10.1016/j.ccr.2006.04.023. Cancer Cell. 2006. PMID: 16766262 Free article.

6

A cytoskeleton-based functional genetic screen identifies Bcl-xL as an enhancer of metastasis, but not primary tumor growth.

Martin SS, Ridgeway AG, Pinkas J, Lu Y, Reginato MJ, Koh EY, Michelman M, Daley GQ, Brugge JS, Leder P. Martin SS, et al. Among authors: leder p. Oncogene. 2004 Jun 3;23(26):4641-5. doi: 10.1038/sj.onc.1207595. Oncogene. 2004. PMID: 15064711

7

P53 levels determine outcome during beta-catenin tumor initiation and metastasis in the mammary gland and male germ cells.

Ridgeway AG, McMenamin J, Leder P. Ridgeway AG, et al. Among authors: leder p. Oncogene. 2006 Jun 15;25(25):3518-27. doi: 10.1038/sj.onc.1209391. Epub 2006 Jan 23. Oncogene. 2006. PMID: 16434961

8

Genome-wide SNP analysis of Tg.AC transgenic mice reveals an oncogenic collaboration between v-Ha-ras and Ink4a, which is absent in p53 deficiency.

Leder A, McMenamin J, Zhou F, Moran JL, Beier DR, Leder P. Leder A, et al. Among authors: leder p. Oncogene. 2008 Apr 10;27(17):2456-65. doi: 10.1038/sj.onc.1210866. Epub 2007 Oct 22. Oncogene. 2008. PMID: 17952114

9

beta-catenin is a downstream effector of Wnt-mediated tumorigenesis in the mammary gland.

Michaelson JS, Leder P. Michaelson JS, et al. Among authors: leder p. Oncogene. 2001 Aug 23;20(37):5093-9. doi: 10.1038/sj.onc.1204586. Oncogene. 2001. PMID: 11526497

10

The oncogene heregulin induces apoptosis in breast epithelial cells and tumors.

Weinstein EJ, Grimm S, Leder P. Weinstein EJ, et al. Among authors: leder p. Oncogene. 1998 Oct 22;17(16):2107-13. doi: 10.1038/sj.onc.1202428. Oncogene. 1998. PMID: 9798682

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