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Page 1
EUK-8, a superoxide dismutase and catalase mimetic, reduces cardiac oxidative stress and ameliorates pressure overload-induced heart failure in the harlequin mouse mutant.
van Empel VP, Bertrand AT, van Oort RJ, van der Nagel R, Engelen M, van Rijen HV, Doevendans PA, Crijns HJ, Ackerman SL, Sluiter W, De Windt LJ. van Empel VP, et al. Among authors: van rijen hv, van der nagel r, van oort rj. J Am Coll Cardiol. 2006 Aug 15;48(4):824-32. doi: 10.1016/j.jacc.2006.02.075. Epub 2006 Jul 25. J Am Coll Cardiol. 2006. PMID: 16904556 Free article.
In calcineurin-induced cardiac hypertrophy expression of Nav1.5, Cx40 and Cx43 is reduced by different mechanisms.
Bierhuizen MF, Boulaksil M, van Stuijvenberg L, van der Nagel R, Jansen AT, Mutsaers NA, Yildirim C, van Veen TA, de Windt LJ, Vos MA, van Rijen HV. Bierhuizen MF, et al. Among authors: van rijen hv, van stuijvenberg l, van der nagel r, van veen ta. J Mol Cell Cardiol. 2008 Sep;45(3):373-84. doi: 10.1016/j.yjmcc.2008.06.011. Epub 2008 Jul 11. J Mol Cell Cardiol. 2008. PMID: 18662696
Heterogeneous Connexin43 distribution in heart failure is associated with dispersed conduction and enhanced susceptibility to ventricular arrhythmias.
Boulaksil M, Winckels SK, Engelen MA, Stein M, van Veen TA, Jansen JA, Linnenbank AC, Bierhuizen MF, Groenewegen WA, van Oosterhout MF, Kirkels JH, de Jonge N, Varró A, Vos MA, de Bakker JM, van Rijen HV. Boulaksil M, et al. Among authors: van rijen hv, van oosterhout mf, van veen ta. Eur J Heart Fail. 2010 Sep;12(9):913-21. doi: 10.1093/eurjhf/hfq092. Epub 2010 Jun 9. Eur J Heart Fail. 2010. PMID: 20534605 Free article.
Mesenchymal stem cell-derived exosomes increase ATP levels, decrease oxidative stress and activate PI3K/Akt pathway to enhance myocardial viability and prevent adverse remodeling after myocardial ischemia/reperfusion injury.
Arslan F, Lai RC, Smeets MB, Akeroyd L, Choo A, Aguor EN, Timmers L, van Rijen HV, Doevendans PA, Pasterkamp G, Lim SK, de Kleijn DP. Arslan F, et al. Among authors: van rijen hv. Stem Cell Res. 2013 May;10(3):301-12. doi: 10.1016/j.scr.2013.01.002. Epub 2013 Jan 14. Stem Cell Res. 2013. PMID: 23399448 Free article.
Reduced Cx43 expression triggers increased fibrosis due to enhanced fibroblast activity.
Jansen JA, van Veen TA, de Jong S, van der Nagel R, van Stuijvenberg L, Driessen H, Labzowski R, Oefner CM, Bosch AA, Nguyen TQ, Goldschmeding R, Vos MA, de Bakker JM, van Rijen HV. Jansen JA, et al. Among authors: van rijen hv, van stuijvenberg l, van der nagel r, van veen ta. Circ Arrhythm Electrophysiol. 2012 Apr;5(2):380-90. doi: 10.1161/CIRCEP.111.966580. Epub 2012 Feb 24. Circ Arrhythm Electrophysiol. 2012. PMID: 22368123
Changes in Cx43 and NaV1.5 expression precede the occurrence of substantial fibrosis in calcineurin-induced murine cardiac hypertrophy.
Fontes MS, Raaijmakers AJ, van Doorn T, Kok B, Nieuwenhuis S, van der Nagel R, Vos MA, de Boer TP, van Rijen HV, Bierhuizen MF. Fontes MS, et al. Among authors: van doorn t, van rijen hv, van der nagel r. PLoS One. 2014 Jan 31;9(1):e87226. doi: 10.1371/journal.pone.0087226. eCollection 2014. PLoS One. 2014. PMID: 24498049 Free PMC article.
Spatial Heterogeneity of Cx43 is an Arrhythmogenic Substrate of Polymorphic Ventricular Tachycardias during Compensated Cardiac Hypertrophy in Rats.
Boulaksil M, Bierhuizen MF, Engelen MA, Stein M, Kok BJ, van Amersfoorth SC, Vos MA, van Rijen HV, de Bakker JM, van Veen TA. Boulaksil M, et al. Among authors: van rijen hv, van amersfoorth sc, van veen ta. Front Cardiovasc Med. 2016 Mar 2;3:5. doi: 10.3389/fcvm.2016.00005. eCollection 2016. Front Cardiovasc Med. 2016. PMID: 26973841 Free PMC article.
Cardiomyocyte-restricted deletion of connexin43 during mouse development.
Eckardt D, Kirchhoff S, Kim JS, Degen J, Theis M, Ott T, Wiesmann F, Doevendans PA, Lamers WH, de Bakker JM, van Rijen HV, Schneider MD, Willecke K. Eckardt D, et al. Among authors: van rijen hv. J Mol Cell Cardiol. 2006 Dec;41(6):963-71. doi: 10.1016/j.yjmcc.2006.07.017. Epub 2006 Sep 11. J Mol Cell Cardiol. 2006. PMID: 16963078
Dominant arrhythmia vulnerability of the right ventricle in senescent mice.
Stein M, Noorman M, van Veen TA, Herold E, Engelen MA, Boulaksil M, Antoons G, Jansen JA, van Oosterhout MF, Hauer RN, de Bakker JM, van Rijen HV. Stein M, et al. Among authors: van rijen hv, van oosterhout mf, van veen ta. Heart Rhythm. 2008 Mar;5(3):438-48. doi: 10.1016/j.hrthm.2007.10.033. Epub 2007 Oct 23. Heart Rhythm. 2008. PMID: 18313604
80 results